Results 131 to 140 of about 34,162 (142)

Ethylmethylhydroxypyridine Succinate Enhances Analgesic Effect of Cyclooxygenase Inhibitors in Rats With Postoperative Hyperalgesia

Russian Journal of Pain
Objective. To evaluate the effect of the antioxidant ethylmethylhydroxypyridine succinate (EMHPS) on the analgesic effects of cyclooxygenase (COX) inhibitors in a model of postoperative hyperalgesia in rats. Material and methods. Mechanical (von Frey test) hyperalgesia in the surgical suture area and metatarsus of rats was recorded for 4 days after ...
Elena A. Ivanova, A G Vasilchuk
exaly   +2 more sources

Evaluation of the effect of ethylmethylhydroxypyridine succinate on the activity of the BCRP transporter protein in vitro

Pharmacokinetics and Pharmacodynamics
Relevance. Breast cancer resistance protein (BCRP) is one of the main clinically significant transporter proteins that play an important role in the pharmacokinetics of drugs. To predict the development of drug interactions at the level of this transporter, it is recommended to test drugs for belonging to ...
M. I. Povetko, P. Yu. Mylnikov, A. V. Shchulkin, E. N. Yakusheva   +3 more
openaire   +1 more source

[he use ethylmethylhydroxypyridine succinate in the treatment of patients with heart failure].

Kardiologiia, 2011
We studied impact of ethylmethylhydroxypyridine succinate n the course of chronic heart failure during 3 years follow-up after myocardial infarction. Dynamics of objective and subjective parameters was assessed in 100 patients; 48 patients received conventional therapy (control group) and 52 patients received conventional therapy plus ...
G I, Sidorenko, S M, Komissarova, S F, Zolotukhina, M E, Petrovskaia   +3 more
openaire   +1 more source

Evaluation of the drug-drug interaction between rivaroxaban and ethylmethylhydroxypyridine succinate in an in vivo experiment

Bulletin of Experimental Biology and Medicine
В исследовании на кроликах-самцах породы советская шиншилла изучено взаимодействие нового орального антикоагулянта ривароксабана и этилметилгидроксипиридина сукцината (ЭМГПС). Ривароксабан вводили кроликам внутрижелудочно в дозе 3 мг/кг однократно, после чего оценивали его концентрацию в плазме крови и протромбиновое время.
M. I. Povetko, P. Yu. Mylnikov, A. V. Shchulkin, I. V. Chernykh, E. N. Yakusheva   +4 more
openaire   +1 more source

EFFICACY OF ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE-BASED PREPARATIONS:

Pharmateca, 2018
openaire   +1 more source

Multimodal effect of ethylmethylhydroxypyridine succinate in the intensive care of patients with multiple organs dysregulation

Фармакология & Фармакотерапия, 2022
Evgenia V. VERIZHNIKOVA, L.M. DOROSHENKO, A.V. CHANTURIDZE   +2 more
openaire   +1 more source

Validated HPLC-MS/MS Method for Quantification of Ethylmethylhydroxypyridine Succinate in Rat Brain and Its Application to a Pharmacokinetic Study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018
Galina Ramenskaya, Alexey Petukhov, Elizaveta Melnik   +2 more
exaly  

[Clinical-immunological aspects of multiple sclerosis treatment with ethylmethylhydroxypyridine succinate].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011
N F, Popova, E V, Orlova, M A, Pashchenkov, A N, Boĭko   +3 more
openaire   +1 more source

Evidence Base of Ethylmethylhydroxypyridine Succinate Use in Patients With Stroke and Its Consequences

Rational Pharmacotherapy in Cardiology, 2014
exaly  

Unification of Procedures for Determining Pharmaceutical Substances Bearing Ionogenic Acidic and Basic Groups, Tranexamic Acid, Ampasse, and Ethylmethylhydroxypyridine Succinate by Reversed-Phase HPLC

Journal of Analytical Chemistry, 2014
exaly