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Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology, 2021
Y. I. Kirova +2 more
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Y. I. Kirova +2 more
exaly +2 more sources
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology, 2023
In the aging and the development of age-associated diseases, the trigger mechanism is the hyperactivation of the hypothalamic-pituitary-adrenal neuroendocrine axis, hypersecretion of glucocorticoids, which, under excessive and long-term stimulation, have inflammatory and degenerative effects. Chronic stress exacerbates glucocorticoid-dependent atrophic
O. L. Terekhina, Y. I. Kirova
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In the aging and the development of age-associated diseases, the trigger mechanism is the hyperactivation of the hypothalamic-pituitary-adrenal neuroendocrine axis, hypersecretion of glucocorticoids, which, under excessive and long-term stimulation, have inflammatory and degenerative effects. Chronic stress exacerbates glucocorticoid-dependent atrophic
O. L. Terekhina, Y. I. Kirova
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Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020
Arterial hypertension, diabetes mellitus, obesity and dyslipidemia continue to be the main risk factors for diseases of the circulatory system and the leading causes of mortality in the world, the combination of these diseases significantly increases the likelihood of the development and more rapid progression of cardiovascular and cerebrovascular ...
E V, Ekusheva, E V, Biryukova
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Arterial hypertension, diabetes mellitus, obesity and dyslipidemia continue to be the main risk factors for diseases of the circulatory system and the leading causes of mortality in the world, the combination of these diseases significantly increases the likelihood of the development and more rapid progression of cardiovascular and cerebrovascular ...
E V, Ekusheva, E V, Biryukova
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effect of Ethylmethylhydroxypyridine succinate (EMS) on brain degeneration in MS
2016Journal of International Society of Antioxidants in Nutrition & Health, Vol 3, No 3 (2016)
Prakhova, Lidia +4 more
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Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2022
Chronic cerebral ischemia (CCI) is a common syndrome that, in the absence of adequate therapy, is characterized by a progressive course, an increase in cognitive, emotional, motor and other disorders, eventually leading to persistent disability of the patient.
M.V. Zhuravleva +6 more
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Chronic cerebral ischemia (CCI) is a common syndrome that, in the absence of adequate therapy, is characterized by a progressive course, an increase in cognitive, emotional, motor and other disorders, eventually leading to persistent disability of the patient.
M.V. Zhuravleva +6 more
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Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2010
A PURPOSE OF THE STUDY: Was to define a degree of quality of a life of patients with chronic pancreatitis by means of the scale SF-36 and also to analyse influence of medicine EMGPS on a quality of a life, level of anxiety and results of clinic-biochemical factors.Biochemical investigations were done on automatic analyzer, alpha-amylase of blood and ...
A G, Samarin, L T, Pimenov
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A PURPOSE OF THE STUDY: Was to define a degree of quality of a life of patients with chronic pancreatitis by means of the scale SF-36 and also to analyse influence of medicine EMGPS on a quality of a life, level of anxiety and results of clinic-biochemical factors.Biochemical investigations were done on automatic analyzer, alpha-amylase of blood and ...
A G, Samarin, L T, Pimenov
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Ethylmethylhydroxypyridine succinate and evidence-based neuroprotection: trends and perspectives
Medical alphabetArterial hypertension (AH) is a leading risk factor for cardiovascular disease, including cerebrovascular events. Damage to the brain as a target organ of AH manifests itself in vascular cognitive impairment (VCI) of varying severity, as well as the development of associated conditions in the form of acute cerebrovascular disorders.
O. D. Ostroumova +4 more
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Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2016
To investigate experimentally in vitro the antioxidant and anti-radical activity of several drugs.Antioxidant activity was assessed by induced luminol-dependent chemiluminescence (CL). An impact on the generation of reactive oxygen species (O2-, OH, 1D, H2O2, HClO) and their ability to inhibit the auto-oxidation of quercetin combined with the ...
Trofimova S, A +3 more
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To investigate experimentally in vitro the antioxidant and anti-radical activity of several drugs.Antioxidant activity was assessed by induced luminol-dependent chemiluminescence (CL). An impact on the generation of reactive oxygen species (O2-, OH, 1D, H2O2, HClO) and their ability to inhibit the auto-oxidation of quercetin combined with the ...
Trofimova S, A +3 more
openaire +2 more sources
Pharmaceutical Chemistry Journal, 2020
The antioxidant formulation ethylmethylhydroxypyridine succinate (Mexidol) effectively neutralizes the radiolysis products of water and oxidative damage to DNA and proteins induced by X-irradiation. This substance was found to affect the formation of long-lived reactive forms of albumins and globulins and their degradation, which is accompanied by ...
E. E. Karmanova +3 more
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The antioxidant formulation ethylmethylhydroxypyridine succinate (Mexidol) effectively neutralizes the radiolysis products of water and oxidative damage to DNA and proteins induced by X-irradiation. This substance was found to affect the formation of long-lived reactive forms of albumins and globulins and their degradation, which is accompanied by ...
E. E. Karmanova +3 more
openaire +1 more source
Possible Use of Ethylmethylhydroxypyridine Succinate (Mexidol) Off-Label as a Radiomodulator
Радиационная биология. Радиоэкология / Radiation biology. Radioecology2-Ethyl-6-methyl-3-hydroxypyridine succinate (EMHPS), the original domestic drug Mexidol, combines anti-hypoxic and antioxidant properties and is actively used in clinical practice in the treatment of various pathologies associated with oxidative stress. Today, the range of its applications is rapidly expanding.
E. E. Karmanova +5 more
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