Results 11 to 20 of about 15,180 (187)
Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells. [PDF]
PLoS ONE, 2015 Etomidate is a rapid hypnotic intravenous anesthetic agent. The major side effect of etomidate is the reduced plasma concentration of corticosteroids, leading to the abnormal reaction of adrenals.
Hua-Cheng Liu +10 more
doaj +1 more source
Archives of Anesthesia and Critical Care, 2021 Background: The very idea of faster recovery and early ambulation has prompted patients to opt for day care surgeries. The concept of ERAS (enhanced recovery after surgery) is the backbone to achieve this goal.
Jyoti Kale +3 more
doaj +1 more source
Brazilian Journal of Anesthesiology, 2022 Background: Though hemodynamically stable, etomidate is known for its myoclonus side effect following induction. The main aim of this study is an effective attempt to decrease the incidence of myoclonus with a priming agent.
Srilata Moningi +5 more
doaj +1 more source
Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats
BMC Pharmacology and Toxicology, 2019 Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects.
Megan McGrath +2 more
doaj +1 more source
Journal of Anaesthesiology Clinical Pharmacology, 2022 Background and Aims: Studies comparing the effect of propofol and etomidate on hemodynamic parameters during electroconvulsive therapy (ECT) have shown ambiguous results.
Divya Mehta +3 more
doaj +1 more source
Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in cushing's syndrome [PDF]
, 1988 We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal adenoma,n=1). Etomidate was given as a continuous infusion for 32
Allolio, B. +5 more
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GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity [PDF]
, 2010 Gap junctions within the cerebral cortex may facilitate cortical seizure formation by their ability to synchronize electrical activity. To investigate this, one option is to compare wild-type (WT) animals with those lacking the gene for connexin36 (Cx36 ...
Jacobson, Gregory M. +3 more
core +2 more sources
BMC Anesthesiology, 2023 Background Etomidate is an imidazole derivative that is widely used in the emergency department for Rapid Sequence Intubation (RSI). Although it has a safe hemodynamic profile, there are some concerns about its suppressant effects on the adreno-cortical ...
Jafar Rahimi Panahi +5 more
doaj +1 more source
Libyan Journal of Medicine, 2023 Etomidate is an anesthetic agent used in hemodynamically unstable patients, but its use has been controversial in septic patients. The response of high-mobility group box 1 (HMGB1), a late-phase lethal cytokine in sepsis, to etomidate has not been ...
Yoo Jung Park +6 more
doaj +1 more source
The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition [PDF]
, 2014 Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a
Alkire +57 more
core +3 more sources