Results 21 to 30 of about 15,180 (187)

Outstanding Seizure Characteristics With Etomidate and Ketofol

open access: yesEuropean Psychiatry, 2022
Introduction Electroconvulsive therapy (ECT) is administered following general anaesthetic induction with methohexital, thiopental, etomidate, alfentanil, remifentanil, propofol or ketamine.
H.C. Özden, S.C. Gurel
doaj   +1 more source

High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]

open access: yes, 2018
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E.   +12 more
core   +1 more source

Safety and efficacy of etomidate and propofol anesthesia in elderly patients undergoing gastroscopy: A double-blind randomized clinical study [PDF]

open access: yes, 2016
The aim of the present study is to compare the safety, efficacy and cost effectiveness of anesthetic regimens by compound, using etomidate and propofol in elderly patients undergoing gastroscopy.
Cao, Chen   +10 more
core   +2 more sources

To Tube or Not to Tube? The Role of Intubation during Stroke Thrombectomy. [PDF]

open access: yes, 2014
In the 10 years since the FDA first cleared the use of endovascular devices for the treatment of acute stroke, definitive evidence that such therapy improves outcomes remains lacking.
Hinman, Jason D   +3 more
core   +2 more sources

One single dose of etomidate negatively influences adrenocortical performance for at least 24 h in children with meningococcal sepsis [PDF]

open access: yes, 2008
Objective: To investigate the effect of one single bolus of etomidate used for intubation on adrenal function in children with meningococcal sepsis. Design: Retrospective study conducted between 1997 and 2004.
Brinker, M. (Marieke) den   +5 more
core   +1 more source

To study the effect of three different doses of dexmedetomidine as premedication on the incidence and severity of etomidate-induced myoclonus

open access: yesThe Indian Anaesthetists' Forum, 2023
Background and Aims: Etomidate, a carboxylated imidazole is a rapid-acting nonbarbiturate, nonopioid hypnotic agent that has unique hemodynamic stability, favorable toxic profile, and rapid recovery after a single dose.
Ketki Kaushal   +3 more
doaj   +1 more source

Minimum infusion rate and adrenocortical function after continuous infusion of the novel etomidate analog ET-26-HCl in rats [PDF]

open access: yesPeerJ, 2017
Background Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate ...
Junli Jiang   +5 more
doaj   +2 more sources

Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]

open access: yes, 2020
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia   +3 more
core   +1 more source

His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]

open access: yes, 1988
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M.   +3 more
core   +1 more source

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