Results 71 to 80 of about 25,547 (271)

Determination of Isavuconazole Susceptibility of Aspergillus and Candida Species by the EUCAST Method [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT Isavuconazole is a novel expanded-spectrum triazole, which has recently been approved by the FDA as an orphan drug to treat invasive aspergillosis and is currently being studied in phase III clinical trials for invasive candidiasis. The susceptibility of relatively few clinical isolates has been reported.
Susan J, Howard, Cornelia, Lass-Flörl, Manuel, Cuenca-Estrella, Alicia, Gomez-Lopez, Maiken C, Arendrup   +4 more
openaire   +2 more sources

Wild-type MIC distributions and epidemiological cutoff values for 5-flucytosine and Candida species as determined by EUCAST broth microdilution

JAC-Antimicrobial Resistance
Objectives EUCAST has established clinical breakpoints and epidemiological cutoff values (ECOFFs) for Candida spp. However, limited data are available for 5-flucytosine (5-FC). We assessed the in vitro susceptibility of 5-FC against a large collection of
Fatima Zohra Delma, Willem J G Melchers, P. Verweij, Jochem B. Buil   +3 more
semanticscholar   +1 more source

In vitro activity of ibrexafungerp against Candida species isolated from blood cultures. Determination of wild type populations using the EUCAST method.

Clinical Microbiology and Infection, 2021
OBJECTIVES Ibrexafungerp is a new oral glucan synthase inhibitor with in vivo and in vitro activity against Candida spp, including echinocandin- and azole-resistant isolates.
Aina Mesquida, Judith Díaz-García, C. Sánchez-Carrillo, P. Muñoz, P. Escribano, J. Guinea   +5 more
semanticscholar   +1 more source

Antifungal susceptibility testing inAspergillusspp. according to EUCAST methodology [PDF]

Medical Mycology, 2006
The availability of new antifungal agents has multiplied the demand for in vitro antifungal susceptibility testing for Aspergillus spp. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) has charged its Antifungal Susceptibility Testing Subcommittee (AFST-EUCAST) with the preparation of new guidelines for in vitro susceptibility ...
Lass-Flörl, C., Cuenca-Estrella, M., Denning, D. W.; id_orcid 0000-0001-5626-2251, Rodriguez-Tudela, J. L.   +3 more
openaire   +2 more sources

In vitro activity of eravacycline and comparators against Gram-negative and Gram-positive bacterial isolates collected from patients globally between 2017 and 2020

Journal of Global Antimicrobial Resistance, 2023
: Objectives: To evaluate eravacycline (ERV) activity against Gram-negative and Gram-positive bacteria collected between 2017 and 2020 from worldwide locations. Methods: MIC determinations were performed using Clinical and Laboratory Standards Institute
Stephen Hawser, Nimmi Kothari, Federica Monti, Ian Morrissey, Sherry Siegert, Tony Hodges   +5 more
doaj   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source

Development of a national EUCAST challenge panel for antimicrobial susceptibility testing [PDF]

Clinical Microbiology and Infection, 2016
A challenge panel of bacterial strains useful for clinical laboratories to validate their European Committee on Antimicrobial Susceptibility Testing (EUCAST) antimicrobial susceptibility test (AST) system was established. A total of 117 strains, obtained from Belgian Reference Centres (n = 57) and from routine clinical samples (n = 60) was selected ...
Desmet, Stefanie, Verhagen, Jan, Glupczynski, Youri, Van Eldere, Johan, MELIN, Pierrette, Goossens, Herman, Pierard, Denis, Declercq, Philippe, Lagrou, Katrien, Boel, Ann, Cartuyvels, Reinoud, Denis, Olivier, Vandewal, Wouter, Saegeman, Veroniek   +13 more
openaire   +6 more sources

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source

Widespread implementation of EUCAST breakpoints for antibacterial susceptibility testing in Europe [PDF]

Eurosurveillance, 2015
The European Committee on Antimicrobial Susceptibility Testing (EUCAST) was established to harmonise clinical antimicrobial breakpoints and to define breakpoints for new agents in Europe. Data from the European Antimicrobial Resistance Surveillance Network (EARS-Net) external quality assessment (EQA) exercises from 2009 to 2012, from the United Kingdom
Brown, D, Canton, R, Dubreuil, L, Gatermann, S, Giske, C, MacGowan, A, Martinez-Martinez, L, Mouton, J, Skov, R, Steinbakk, Martin, Walton, C, Heuer, O, Struelens, M J, Högberg, L Diaz, Kahlmeter, G   +14 more
openaire   +5 more sources

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner, Dennis D. Arnold, Philipp P. Bosshard   +2 more
wiley   +1 more source