Results 51 to 60 of about 25,547 (271)

How to interpret MICs of amphotericin B, echinocandins and flucytosine against Candida auris (Candidozyma auris) according to the newly established EUCAST breakpoints.

Clinical Microbiology and Infection
BACKGROUND Candida auris (Candidozyma auris) has emerged as an important pathogen across all continents, with clonal outbreaks and hospital transmissions. Most isolates are fluconazole resistant and variable resistance rates are reported for amphotericin
M. Arendrup, J. Guinea, S. Arikan‐Akdagli, Eelco F. J. Meijer, J. Meis, Jochem B. Buil, E. Dannaoui, C. Giske, P. Lysková, J. Meletiadis   +9 more
semanticscholar   +1 more source

The EUCAST Disk Diffusion Method for Antimicrobial Susceptibility Testing of Oral Anaerobes

Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)
There is a need for standardized methods for antimicrobial susceptibility testing (AST) of anaerobic bacteria involved in oral and extra‐oral infections.
A. Jensen, E. F. Lau, T. Greve, Niels Nørskov-Lauritsen   +3 more
semanticscholar   +1 more source

The EUCAST rapid disc diffusion method for antimicrobial susceptibility testing directly from positive blood culture bottles

Journal of Antimicrobial Chemotherapy, 2020
Objectives With increasing antimicrobial resistance, rapid antimicrobial susceptibility testing (RAST) becomes important, especially in patients with bloodstream infections.
Emma Jonasson, E. Matuschek, G. Kahlmeter   +2 more
semanticscholar   +1 more source

Multicentre Evaluation of the EUCAST Rapid Antimicrobial Susceptibility Testing (RAST) Extending Analysis to 16–20 Hours Reading Time

Antibiotics, 2022
The aim of the study was to evaluate the EUCAST RAST method by extending analysis to 16–20 h reading time and performance with new β-lactam/β-lactamase inhibitor combinations. A total of 676 positive blood cultures (BCs) were enrolled.
G. Bianco, D. Lombardo, G. Ricciardelli, M. Boattini, S. Comini, R. Cavallo, C. Costa, S. Ambretti   +7 more
semanticscholar   +1 more source

Pan-Echinocandin Resistant C. parapsilosis Harboring an F652S Fks1 Alteration in a Patient with Prolonged Echinocandin Therapy

Journal of Fungi, 2022
The isolation of a pan-echinocandin-resistant Candida parapsilosis strain (anidulafungin, caspofungin, micafungin and rezafungin EUCAST MICs > 8 mg/L) from urine of a patient following prolonged exposure to echinocandins (38 days of micafungin followed ...
Maria Siopi, Antonios Papadopoulos, Anastasia Spiliopoulou, Fotini Paliogianni, Nissrine Abou-Chakra, Maiken Cavling Arendrup, Christina Damoulari, Georgios Tsioulos, Efthymia Giannitsioti, Frantzeska Frantzeskaki, Iraklis Tsangaris, Spyros Pournaras, Joseph Meletiadis   +12 more
doaj   +1 more source

Identification and antifungal susceptibility patterns of reference yeast strains to novel and conventional agents: a comparative study using CLSI, EUCAST and Sensititre YeastOne methods

JAC-Antimicrobial Resistance
Objectives The aim of this study was to identify and determine the MICs of 13 antifungal drugs, including the novel agents ibrexafungerp, manogepix and rezafungin, against 22 laboratory reference strains from 14 different Candida spp.
Andres Ceballos-Garzon, Marion Holzapfel, Jeremy Welsch, D. Mercer   +3 more
semanticscholar   +1 more source

EUCAST rapid antimicrobial susceptibility testing (RAST) in blood cultures: validation in 55 European laboratories

Journal of Antimicrobial Chemotherapy, 2020
Objectives When bloodstream infections are caused by resistant bacteria, rapid antimicrobial susceptibility testing (RAST) is important for adjustment of therapy.
A. Åkerlund, Emma Jonasson, E. Matuschek, L. Serrander, M. Sundqvist, G. Kahlmeter, Esad Dennis Schrøder harlotte Nielsen Anu Raija Juha O Dzajic Hansen Agergaard Pätäri-Sampo Manninen Grön, E. Dzajic, D. S. Hansen, harlotte Nielsen Agergaard, A. Pätäri-Sampo, R. Manninen, J. O. Grönroos, J. Rasigade, Waël Salka, P. Boyer, E. Lebessi, Nikolaos Zapaniotis, E. Petinaki, I. Spiliopoulou, F. Kolonitsiou, K. Helgason, J. Brazil, E. Riccobono, G. Lo Cascio, L. Maccacaro, Helge Kolstad, T. Haukeland, Pirkko-Liisa Kellokumpu, Andreas Fossum Mjøen, Ståle Tofteland, Berit Harbak, S. Hartzen, Siri Haug Hänsgen, K. W. Gammelsrud, Unni Skolbekken, Nina Michalsen, A. Brekken, B. Pedersen, Brian Guennigsman, A. Lia, A. Berg, F. Marco, C. Pitart, P. Egea, J. L. Cortés-Cuevas, J. Machuca, M. Wietzke, Magdalena Dammström, R. Granström, Maria Corneliusson, Marita Skarstedt, Karin Frykfeldt, C. Ivarsson, A. Sergejev, Susanna Hagström, Ulrika Lidén, J. Rydberg, Hanna Ramström, Inga Fröding, E. Petropoulos, Karolina Ininbergs, S. Jalal, A. Persson, N. Kamenska, Kerstin Granlund, Anna-Karin Smekal, Anna Hill, G. Rådberg, G. Heyman, L. Rodriguez, Lisa Vennberg, G. Hazırolan, I. Akyar, Gelmez Gülşen Altınkanat, Ayşe Nur Sarı Kaygısız   +75 more
semanticscholar   +1 more source

Ceftolozane/Tazobactam Activity Against Drug-Resistant Pseudomonas aeruginosa and Enterobacterales Causing Healthcare-Associated Infections in Eight Asian Countries: Report from an Antimicrobial Surveillance Program (2016–2018)

Infection and Drug Resistance, 2022
Michael Pfaller,1,2 Dee Shortridge,1 Wei-Ting Chen,3 Helio Sader,1 Mariana Castanheira1 1JMI Laboratories, North Liberty, IA, USA; 2University of Iowa College of Medicine, Iowa City, IA, USA; 3Merck & Co., Inc, Kenilworth, NJ, USACorrespondence: Dee ...
Pfaller M, Shortridge D, Chen WT, Sader H, Castanheira M   +4 more
doaj  

Time to switch from CLSI to EUCAST? A Southeast Asian perspective [PDF]

Clinical Microbiology and Infection, 2019
Despite the importance of antimicrobial susceptibility testing (AST) to clinical management of infection and to antimicrobial resistance (AMR) surveillance, methodologies and breakpoints of the two most commonly used systems worldwide, CLSI and EUCAST, are far from harmonized.
Cusack, T, Ashley, E, Ling, C, Roberts, T, Turner, P, Wangrangsimakul, T, Dance, D   +6 more
openaire   +2 more sources

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source