Results 51 to 60 of about 11,020,597 (230)
Cas9-mediated targeting of viral RNA in eukaryotic cells
Proceedings of the National Academy of Sciences of the United States of America, 2015 Significance The clustered, regularly interspaced, short palindromic repeats associated endonuclease, Cas9, has quickly become a revolutionary tool in genome engineering.
Aryn A. Price +4 more
semanticscholar +1 more source
“Breaking up is hard to do”: the formation and resolution of sister chromatid intertwines [PDF]
, 2014 The absolute necessity to resolve every intertwine between the two strands of the DNA double helix provides a massive challenge to the cellular processes that duplicate and segregate chromosomes.
Bartkova +110 more
core +1 more source
Evolutionary cell biology: Functional insight from “Endless forms most beautiful” [PDF]
, 2015 In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level.
Dacks, Joel B. +4 more
core +1 more source
Phagocytosis-like cell engulfment by a planctomycete bacterium
Nature Communications, 2019 Phagocytosis is a typically eukaryotic feature that could be behind the origin of eukaryotic cells. Here, the authors describe a bacterium that can engulf other bacteria and small eukaryotic cells through a phagocytosis-like mechanism.
Takashi Shiratori +3 more
doaj +1 more source
Circular RNAs in Eukaryotic Cells
Current Genomics, 2015 Circular RNAs (circRNAs) are now recognized as large species of transcripts in eukaryotic cells. From model organisms such as C. elegans, Drosophila, mice to human beings, thousands of circRNAs formed from back-splicing of exons have been identified. The
Liang Chen +3 more
semanticscholar +1 more source
Bacterial toxin effector membrane targeting: Outside in, then back again.
Frontiers in Cellular and Infection Microbiology, 2012 Pathogenic bacteria utilize multiple approaches to mediate their toxicity to eukaryotic cells. Dedicated protein machines deposit toxic effectors directly inside the host, whereas secreted toxins must enter cells independently of other bacterial ...
Brett eGeissler
doaj +1 more source
Scientific Reports, 2015 Toxin-antitoxin (TA) modules contribute to the generation of non-growing cells in response to stress. These modules abound in bacterial pathogens although the bases for this profusion remain largely unknown.
Damián Lobato-Márquez +4 more
semanticscholar +1 more source
Evolution: functional evolution of nuclear structure. [PDF]
, 2011 The evolution of the nucleus, the defining feature of eukaryotic cells, was long shrouded in speculation and mystery. There is now strong evidence that nuclear pore complexes (NPCs) and nuclear membranes coevolved with the endomembrane system, and that ...
Dawson, Scott C, Wilson, Katherine L
core
Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds [PDF]
, 2007 Tubulin is essential to eukaryotic cells and is targeted by several antineoplastics, herbicides, and antimicrobials. We demonstrate that Acanthamoeba spp.
Henriquez, Fiona L. +4 more
core +2 more sources
Tubular microfossils from ∼2.8 to 2.7Ga-old lacustrine deposits of South Africa: A sign for early origin of eukaryotes? [PDF]
, 2016 Unequivocal evidence for Archean eukaryotic life has been long sought for and is a matter of lively debate. In the absence of unambiguous fossils this debate has focused on biogeochemical signatures and molecular phylogenies.
Altermann, Wladyslaw +3 more
core +2 more sources