Results 31 to 40 of about 248,805 (183)

Zinc Influx Restricts Enterovirus D68 Replication

Frontiers in Microbiology, 2021
Enterovirus D68 (EV-D68) is a respiratory viral pathogen that causes severe respiratory diseases and neurologic manifestations. Since the 2014 outbreak, EV-D68 has been reported to cause severe complications worldwide.
Shunan Liu, Xia Cao, Haoran Guo, Wei Wei
doaj   +1 more source

Pterostilbene, an active constituent of blueberries, enhances innate immune activation and restricts enterovirus D68 infection

Frontiers in Immunology, 2023
Enterovirus D68 (EV-D68) is a globally re-emerging respiratory pathogen implicated in outbreaks of severe respiratory illnesses and associated with acute flaccid myelitis. However, effective vaccines or treatments for EV-D68 infections remain scarce.
Qingran Yang, Huili Li, Zhaoxue Li, Jiaxin Yang, Zhe Zhang, Lili Zhang, Haoran Guo, Wei Wei, Wei Wei   +8 more
doaj   +1 more source

Neutralizing activity of intravenous immune globulin products against enterovirus D68 strains isolated in Japan

BMC Infectious Diseases, 2023
Background Enterovirus D68 (EV-D68), belonging to Enterovirus D, is a unique human enterovirus mainly associated with common respiratory diseases. However, EV-D68 can cause severe respiratory diseases, and EV-D68 endemic is epidemiologically linked to ...
Kazuhiro Yoshida, Masamichi Muramatsu, Hiroyuki Shimizu   +2 more
doaj   +1 more source

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024. [PDF]

J Med Virol
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Camacho J, García-Ibáñez N, Fernández-García MD, Biya Y, Ruiz de Pedro E, Gutiérrez A, Nieto MC, Ruiz-García MM, Pastor-Fajardo MT, Lagarejos E, de Leonardo Simón C, Navascués A, Moreno-Docón A, Gozalo-Marguello M, Berengua C, Antequera P, Huéscar-Pascual MD, Calvo C, Cabrerizo M.   +18 more
europepmc   +2 more sources

Emergence of divergent enterovirus (EV) D68 sub-clade D1 strains, northern Italy, September to October 2018. [PDF]

Euro Surveill, 2019
An enterovirus D68 (EV-D68) outbreak was recognised at a major tertiary centre and research hospital in Milan and Pavia in the Lombardy region, northern Italy, respectively, between September and October 2018.
Pellegrinelli L, Giardina F, Lunghi G, Uceda Renteria SC, Greco L, Fratini A, Galli C, Piralla A, Binda S, Pariani E, Baldanti F.   +10 more
europepmc   +2 more sources

Apical-out airway organoids are susceptible to infection with EV-D68

, 2023
 (A) Representative brightfield images showing the cytopathologic effect of EV-D68 infection over 48 h. Infected Ap-O AO organoids disintegrate to single cells over the course of the infection (scale bars = 300 μm).
Georgios Stroulios (12536191)
core   +1 more source

Duration of Enterovirus D68 RNA Shedding in the Upper Respiratory Tract and Transmission among Household Contacts, Colorado, USA

Emerging Infectious Diseases, 2023
Enterovirus D68 (EV-D68) causes cyclical outbreaks of respiratory disease and acute flaccid myelitis. EV-D68 is primarily transmitted through the respiratory route, but the duration of shedding in the respiratory tract is unknown.
Hai Nguyen-Tran, Careese Thompson, Molly Butler, Kristen R. Miller, Laura Pyle, Sarah Jung, Shannon Rogers, Terry Fei Fan Ng, Janell Routh, Samuel R. Dominguez, Kevin Messacar   +10 more
doaj   +1 more source

Structure and inhibition of EV-D68, a virus that causes respiratory illness in children [PDF]

Science, 2015
Targeting EV-D68, a respiratory virus A recent outbreak of respiratory illness in U.S. children was caused by entorovirus D68 (EV-D68). Enteroviruses also include human pathogens such as human rhinovirus, which causes the common cold, and poliovirus. Most of these viruses are stabilized by a factor that binds in a
Yue, Liu, Ju, Sheng, Andrei, Fokine, Geng, Meng, Woong-Hee, Shin, Feng, Long, Richard J, Kuhn, Daisuke, Kihara, Michael G, Rossmann   +8 more
openaire   +2 more sources

EV-D68 cleaves LARP1 and PABPC1 by 3Cpro to redirect host mRNA translation machinery toward its genomic RNA. [PDF]

PLoS Pathog
Enterovirus D68 (EV-D68) is an emerging pathogen associated with severe respiratory diseases and neurological complications, such as acute flaccid myelitis.
Tan R, Zhang Y, Huang M, Chen H, Liu Z, Wang Z, Li X, Wang T, Wang Z.   +8 more
europepmc   +2 more sources

Enterovirus (EV) D68 TaqMan 2018 (EV-D68-TM2018) v1 [PDF]

, 2018
This protocol aims to amplify enterovirus (EV) D68 viruses and not other viruses. This protocol is modified from a previously published method cited below. Details of the modification are included in the method. The oligonucleotides target the 5'UTR noncoding region. This is a qualitative test for investigating EV-D68 infection of humans.
Ian M Mackay, Judy A Northill
openaire   +1 more source