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Enterovirus (EV) D68 real-time RT-PCR (EV-D68-TM2018) v2 [PDF]

open access: yes, 2019
This protocol aims to amplify enterovirus (EV) D68 viruses but not other viruses. This protocol is modified from a previously published method cited below. Details of the modification are included in the method. The oligonucleotides target the 5'UTR noncoding region. This is a qualitative test for investigating EV-D68 infection of humans.
Ian M Mackay, Judy A Northill
openaire   +1 more source

Genomic analysis of enterovirus D68, including one strain isolated from a child with Wilson's disease in Taiwan

open access: yesJournal of the Formosan Medical Association, 2019
North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained
Yeh-Sheng Chien   +6 more
doaj   +1 more source

CD74 Interacts with Proteins of Enterovirus D68 To Inhibit Virus Replication

open access: yesMicrobiology Spectrum, 2023
Enterovirus D68 (EV-D68) is a member of the species Enterovirus D in the genus Enterovirus of the family Picornaviridae. As an emerging non-polio enterovirus, EV-D68 is widely spread all over the world and causes severe neurological and respiratory ...
Zichun Xiang   +8 more
doaj   +1 more source

Enterovirus D68 in Hospitalized Children: Sequence Variation, Viral Loads and Clinical Outcomes.

open access: yesPLoS ONE, 2016
BackgroundAn outbreak of enterovirus D68 (EV-D68) caused severe respiratory illness in 2014. The disease spectrum of EV-D68 infections in children with underlying medical conditions other than asthma, the role of EV-D68 loads on clinical illness, and the
Katherine Moyer   +4 more
doaj   +1 more source

Acute flaccid myelitis associated with enterovirus D68 in a non-epidemic setting

open access: yesIDCases, 2019
Acute flaccid myelitis (AFM) is a recently defined clinical disease accompanied by the national outbreak of enterovirus D68 (EV-D68) in the United States during the late summer/fall of 2014; 258 cases of EV-D68 and 59 cases of AFM were reported in Japan ...
Kazuki Hatayama   +8 more
doaj   +1 more source

Long non-coding RNA SNHG9 regulates viral replication in rhabdomyosarcoma cells infected with enterovirus D68 via miR-150-5p/c-Fos axis

open access: yesFrontiers in Microbiology, 2023
BackgroundThe Enterovirus D68 (EV-D68) epidemic has increased knowledge of the virus as a pathogen capable of causing serious respiratory and neurological illnesses.
Huichao Fu   +9 more
doaj   +1 more source

Enterovirus D68-associated respiratory and neurological illness in Spain, 2014–2018

open access: yesEmerging Microbes and Infections, 2019
During 2014, enterovirus D68 (EV-D68) outbreaks were described globally, causing severe respiratory diseases in children and, in some cases, subsequent paralysis.
Rubén González-Sanz   +11 more
doaj   +1 more source

Enterovirus D68 virus-like particles expressed in Pichia pastoris potently induce neutralizing antibody responses and confer protection against lethal viral infection in mice

open access: yesEmerging Microbes and Infections, 2018
Enterovirus D68 (EV-D68) has been increasingly associated with severe respiratory illness and neurological complications in children worldwide. However, no vaccine is currently available to prevent EV-D68 infection.
Chao Zhang   +11 more
doaj   +1 more source

Enterovirus D-68 Infection of Primary Rat Cortical Neurons: Entry, Replication, and Functional Consequences

open access: yesmBio, 2023
Enterovirus D68 (EV-D68) is an emerging pathogen associated with mild to severe respiratory disease. Since 2014, EV-D68 is also linked to acute flaccid myelitis (AFM), causing paralysis and muscle weakness in children. However, it remains unclear whether
Katrien C. K. Poelaert   +11 more
doaj   +1 more source

Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis

open access: yesPLoS Neglected Tropical Diseases, 2022
A substantial amount of epidemiological data has been reported on Enterovirus D68 (EV-D68) infections after the 2014 outbreak. Our goal was to map the case fatality rate (CFR) and prevalence of current and past EV-D68 infections.
Amary Fall   +33 more
doaj  

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