Results 51 to 60 of about 1,484 (240)
A generalization of first direct method of pursuit for differential inclu-sions
Міжнародний науково-технічний журнал "Проблеми керування та інформатики", 2023 To solve the problem of pursuit in linear differential games, L.S. Pontryagin suggested two direct methods. Direct methods are of great importance in the development of the theory of differential games and in control theory under the conditions of ...
Ікромжон Мадашевич Ісканаджієв
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Two Hierarchical Guidance Laws of Pursuer in Orbital Pursuit–Evasion–Defense Game
Aerospace, 2023 In this study, differential game theory was applied to propose two guidance laws of a pursuer in an orbit pursuit–evasion–defense game. One was a conservative guidance law of maneuvering to absolute safety before pursuing the evader, and the other was a ...
Yongshang Wei +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Cooperative Multiple Pursuers against a Single Evader
, 2017 \ua9 2016, Springer Science+Business Media Dordrecht.This paper considers a pursuit-evasion game for non-holonomic systems where a group of pursuers attempts to capture an evader in a bounded connected domain.
Manathara JG, Kothari M, Postlethwaite I
core +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Evader Surveillance Under Incomplete Information [PDF]
, 2009 — This paper is concerned with determining whether a mobile robot, called the pursuer , is up to maintain- ing visibility of an antagonist agent, called the evader . This problem, a variant of pursuit-evasion , has been largely studied,
RAFAEL ERIC MURRIETA CID
core
A pursuer-evader game for sensor networks
, 2003 . In this paper a self-stabilizing program for solving a pursuer-evader problem in sensor networks is presented. The program can be tuned for tracking speed or energy efficiency.
Murat Demirbas +2 more
core +1 more source