Results 71 to 80 of about 5,205 (290)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Solution of a Linear Pursuit-Evasion Differential Game with Closed and Convex Terminal Set
Journal of Mathematical and Fundamental Sciences, 2013 A linear two-person zero-sum pursuit-evasion differential game is considered. Control functions of players are subject to integral constraints. Terminal set is a closed convex subset of The Pursuer tries to bring the state of the system to the terminal ...
Gafurjan I. Ibragimov +2 more
doaj +1 more source
Deep Reinforcement Learning for Swarm Systems
, 2019 Recently, deep reinforcement learning (RL) methods have been applied successfully to multi-agent scenarios. Typically, these methods rely on a concatenation of agent states to represent the information content required for decentralized decision making ...
Hüttenrauch, Maximilian +2 more
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Sciential - McMaster Undergraduate Science Journal, 2018 The CRISPR-Cas9 system has paved the way for realizing gene-editing, but its main weakness lies in its potential for off-target effects. Studies into phages reveal that they express “anti-CRISPR” proteins which if harnessed, could provide us with the solution to this lack of control.
openaire +2 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
AerospaceAiming to address the problem of pursuit and interception for spacecraft using multiple evasion strategies, a pursuit strategy involving the use of an interactive multiple-model filter (IMM) in a pursuit–evasion game is considered, where the Evader ...
Chuangge Wang, Danhe Chen, Wenhe Liao
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Hide and Seek in Arizona [PDF]
Laboratory subjects repeatedly played one of two variations of a simple two-person zero-sum game of ``hide and seek.'' Three puzzling departures from the prescriptions of equilibrium theory are found in the data: an asymmetry related to the player's role
Jason Shachat +2 more
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Differential game with many pursuers when controls are subjected to coordinate-wise integral constraints [PDF]
, 2016 In this paper, we study a differential game of many pursuers and one evader in R2. The motions of all players are simple. An integral constraint is imposed on each coordinate of the control functions of players.
Alias, Idham Arif +3 more
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