Results 81 to 90 of about 1,484 (240)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Research on Pursuit-evasion Games with Multiple Heterogeneous Pursuers and A High Speed Evader
, 2015 We deal with Pursuit-evasion games with a high speed evader which has superiority in velocity over a group of heterogeneous pursuers in this paper. Heterogeneity in the group of pursuers is expressed as heterogeneity in the individual maximum speeds.
Liu JT(刘景泰) +2 more
core
Mode-switching cooperative defense strategy for the orbit pursuit-evasion-defense game
Defence TechnologyThis paper presents a mode-switching collaborative defense strategy for spacecraft pursuit-evasion-defense scenarios. In these scenarios, the pursuer tries to avoid the defender while capturing the evader, while the evader and defender form an alliance ...
Yongshang Wei, Tianxi Liu, Cheng Wei
doaj +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Cooperative pursuit with multi-pursuer and one faster free-moving evader
, 2020 This paper addresses a multi-pursuer single-evader pursuit-evasion game where the free-moving evader moves faster than the pursuers. Most of the existing works impose constraints on the faster evader such as limited moving area and moving direction. When
Fang, Xu +3 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Optimizing evasive strategies for an evader with imperfect vision capacity
, 2019 The multiagent pursuit-evasion problem has attracted considerable interest during recent years, and a general assumption is that the evader has perfect vision capacity.
Yang, Shaofu +6 more
core +1 more source
Simple Motion Evasion Differential Game of One Pursuer and One Evader [PDF]
, 2016 We study an evasion differential game of simple motion, involving one pursuer and one evader in the plane R². The control functions of players are subjected to geometric constraints.
Syed Mafdzot, Sharifah Anisah +5 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source