Results 101 to 110 of about 57,905 (241)

Does organizational justice facet matters in knowledge hiding? [PDF]

open access: yesHeliyon, 2023
Mahmood H   +5 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

A virologist’s guide to hide and seek : evasion of innate immunity by primate lentiviruses

open access: yes, 2015
HIV is the cause of a chronic, incurable infection in 37 million people worldwide in 2014. This thesis investigates how the immune system detects HIV and how in turn HIV avoids detection by the immune system. The understanding of the viral evasion mechanisms that prevent immune detection (“Hide and Seek”) is important to successfully develop future ...
openaire   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu   +2 more
wiley   +1 more source

Dynamic Performance Enhancement of a High‐Agility Hypersonic Mechanical System via a Learning‐Augmented Robust Control Architecture

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT The design of control systems for high‐agility mechanical systems operating in extreme environments is a significant challenge in nonlinear dynamics. This paper addresses the complex dynamic control problem of a hypersonic interceptor, modeled as a multi‐input multi‐output (MIMO) mechanical system characterized by strong aerodynamic cross ...
Mohammad Mahdi Soori   +1 more
wiley   +1 more source

Information Hiding in Product Development: The Design Churn Effect

open access: yes, 2002
Execution of a complex product development project is facilitated through its decomposition into an interrelated set of localized development tasks.
Yassine, Ali   +4 more
core  

Safeguarded Reinforcement Learning for Dynamic Environments

open access: yesOptimal Control Applications and Methods, EarlyView.
This paper uses a combination of Reinforcement Learning and Funnel Control to train a fast and safe controller for systems operating in changing environments. Furthermore, the presented formulation overcomes former limitations associated with the need for predefined reference trajectories.
Simon Gottschalk
wiley   +1 more source

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