Results 81 to 90 of about 1,764,141 (282)

Dynamically Driven Evolution of the Interstellar Medium in M51 [PDF]

, 2009
Massive star formation occurs in giant molecular clouds (GMCs); an understanding of the evolution of GMCs is a prerequisite to develop theories of star formation and galaxy evolution. We report the highest-fidelity observations of the grand-design spiral
Bock, Douglas C.-J., Carpenter, John M., Corder, Stuartt A., Hawkins, David, Hodges, Mark, Kemball, Athol, Koda, Jin, La Vigne, Misty A., Lamb, James W., Patience, Jenny, Plambeck, Richard L., Potts, Ashley E., Pound, Marc W., Sargent, Anneila I., Sawada, Tsuyoshi, Scott, Stephen L., Scoville, Nick, Teuben, Peter, Voguel, Stuart N., White, Stephen M., Woody, David P., Wright, Melvyn C. H., Zauderer, B. Ashley   +22 more
core  

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

El origen de la vida y la primera molécula capaz de replicarse a sí misma

Revista de Química, 2014
El origen de la vida en la Tierra es una de las preguntas más difíciles presentadas a la ciencia. En los últimos 60 años, ha habido un progreso considerable en entender cómo moléculas relativamente sencillas, que son relevantes para la vida, pueden ser ...
Roberto Laos, Steven Benner
doaj  

Constraints on the Star-Forming Interstellar Medium in Galaxies Back to the First Billion Years of Cosmic Time [PDF]

, 2011
Constraints on the molecular gas content of galaxies at high redshift are crucial to further our understanding of star formation and galaxy evolution through cosmic times, as molecular gas is the fuel for star formation.
Riechers, Dominik A.
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Molecular characterization of the evolution of phagosomes

Molecular Systems Biology, 2010
Amoeba use phagocytosis to internalize bacteria as a source of nutrients, whereas multicellular organisms utilize this process as a defense mechanism to kill microbes and, in vertebrates, initiate a sustained immune response. By using a large‐scale approach to identify and compare the proteome and phosphoproteome of phagosomes isolated from distant ...
Jonathan Boulais, Pierre Thibault, Matthias Trost, Matthias Trost, Michel Desjardins, Thierry Soldati, Christian R. Landry, Stephen W. Michnick, Emmanuel D. Levy, Régis Dieckmann   +9 more
openaire   +7 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

The distributions of protein coding genes within chromatin domains in relation to human disease

Epigenetics & Chromatin, 2019
Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C.
Enrique M. Muro, Jonas Ibn-Salem, Miguel A. Andrade-Navarro   +2 more
doaj   +1 more source

On the Rapid Collapse and Evolution of Molecular Clouds

, 2007
Stars generally form faster than the ambipolar diffusion time, suggesting that several processes short circuit the delay and promote a rapid collapse.
Bacmann A., Ballesteros-Paredes J., Battinelli P., Bonnell I. A., Bruce G. Elmegreen, Di Fazio A., Efremov Y. N., Elmegreen B. G., Fukui Y., Goldreich P., Greaves J. S., Holland W. S., Honma M., Hujeirat A., Larson R. B., Mestel L., Motte F., Nakamura F., Nakano T., Omont A., Smith M. D., Stutzki J., Tilley D. A., Umebayashi T., Verschueren W., Whitworth A.   +25 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source