Results 11 to 20 of about 145,655 (269)

Engram Excitement [PDF]

open access: yesNeuron, 2019
Engram cells can encode and switch between multiple mnemonic functions, but how they intrinsically do so is unknown. Pignatelli, Ryan, and colleagues show that upon memory recall, the engram's excitability is transiently elevated, allowing its bearer to adapt to changing environments.
Albo, Zimbul, Gräff, Johannes
openaire   +3 more sources

Exciting and not so exciting roles of pannexins [PDF]

open access: yesNeuroscience Letters, 2019
It is the current view that purinergic signaling regulates many physiological functions. Pannexin1 (Panx1), a member of the gap junction family of proteins is an ATP releasing channel that plays important physio-pathological roles in various tissues, including the CNS.
Eliana, Scemes, Jana, Velíšková
openaire   +2 more sources

On the persistency of excitation

open access: yesAutomatica, 2023
Peer ...
Ivan Markovsky   +2 more
openaire   +5 more sources

Response of a Parametrically Excited System to a Nonstationary Excitation [PDF]

open access: yesJournal of Vibration and Control, 1993
The response of a single-degree-of-freedom system to a nonstationary excitation is investigated by using the method of multiple scales as well as analog- and digital-computer simulations. The unexcited system has one focus and two saddle points. The system can be used to model rolling of ships in head or follower seas.
Neal, Harold L., Nayfeh, Ali H.
openaire   +2 more sources

Greater cognitive reserve is related to lower cortical excitability in healthy cognitive aging, but not in early clinical Alzheimer’s disease

open access: yesFrontiers in Human Neuroscience, 2023
ObjectiveTo investigate the relationship between cortico-motor excitability and cognitive reserve (CR) in cognitively unimpaired older adults (CU) and in older adults with mild cognitive impairment or mild dementia due to Alzheimer’s disease (AD ...
Stephanie S. Buss   +16 more
doaj   +1 more source

Homogeneous and Narrow Bandwidth of Spike Initiation in Rat L1 Cortical Interneurons

open access: yesFrontiers in Cellular Neuroscience, 2020
The cortical layer 1 (L1) contains a population of GABAergic interneurons, considered a key component of information integration, processing, and relaying in neocortical networks.
Stefano Borda Bossana   +3 more
doaj   +1 more source

Minimal requirements for a neuron to coregulate many properties and the implications for ion channel correlations and robustness

open access: yeseLife, 2022
Neurons regulate their excitability by adjusting their ion channel levels. Degeneracy – achieving equivalent outcomes (excitability) using different solutions (channel combinations) – facilitates this regulation by enabling a disruptive change in one ...
Jane Yang   +3 more
doaj   +1 more source

Chirp excitation [PDF]

open access: yesJournal of Magnetic Resonance, 2017
The paper describes the design of broadband chirp excitation pulses in NMR. We first develop a three stage model for understanding chirp excitation in NMR. We then show how a chirp $π$ pulse can be used to refocus the phase of the chirp excitation pulse. The resulting magnetization still has some phase dispersion in it. We show how a combination of two
openaire   +3 more sources

Subunit gating resulting from individual protonation events in Kir2 channels

open access: yesNature Communications, 2023
Inwardly rectifying potassium (Kir) channels open at the ‘helix bundle crossing’ (HBC), formed by the M2 helices at the cytoplasmic end of the transmembrane pore.
Grigory Maksaev   +5 more
doaj   +1 more source

THE EXCITEMENT OF DISCOVERY [PDF]

open access: yesAnnual Review of Biochemistry, 2004
I had the good luck to start research at the dawn of molecular biology when it was possible to ask fundamental questions about the nature of the nucleic acids and how information is transferred in living systems. The search for answers led me into many different areas, often with the question of how molecular structure leads to biological function ...
openaire   +2 more sources

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