Results 11 to 20 of about 144,668 (268)

Response of a Parametrically Excited System to a Nonstationary Excitation [PDF]

open access: yesJournal of Vibration and Control, 1993
The response of a single-degree-of-freedom system to a nonstationary excitation is investigated by using the method of multiple scales as well as analog- and digital-computer simulations. The unexcited system has one focus and two saddle points. The system can be used to model rolling of ships in head or follower seas.
Neal, Harold L., Nayfeh, Ali H.
openaire   +2 more sources

The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome

open access: yesFunction, 2020
Dramatic cardiomegaly arising from gain-of-function (GoF) mutations in the ATP-sensitive potassium (KATP) channels genes, ABCC9 and KCNJ8, is a characteristic feature of Cantú syndrome (CS).
Conor McClenaghan   +10 more
doaj   +1 more source

On the persistency of excitation

open access: yesAutomatica, 2023
Peer ...
Ivan Markovsky   +2 more
openaire   +5 more sources

The effects of membrane potential oscillations on the excitability of rat hypoglossal motoneurons

open access: yesFrontiers in Physiology, 2022
Oscillations in membrane potential induced by synaptic inputs and intrinsic ion channel activity play a role in regulating neuronal excitability, but the precise mechanisms underlying their contributions remain largely unknown.
Qiang Zhang   +7 more
doaj   +1 more source

Chirp excitation [PDF]

open access: yesJournal of Magnetic Resonance, 2017
The paper describes the design of broadband chirp excitation pulses in NMR. We first develop a three stage model for understanding chirp excitation in NMR. We then show how a chirp $π$ pulse can be used to refocus the phase of the chirp excitation pulse. The resulting magnetization still has some phase dispersion in it. We show how a combination of two
openaire   +3 more sources

Homogeneous and Narrow Bandwidth of Spike Initiation in Rat L1 Cortical Interneurons

open access: yesFrontiers in Cellular Neuroscience, 2020
The cortical layer 1 (L1) contains a population of GABAergic interneurons, considered a key component of information integration, processing, and relaying in neocortical networks.
Stefano Borda Bossana   +3 more
doaj   +1 more source

Greater cognitive reserve is related to lower cortical excitability in healthy cognitive aging, but not in early clinical Alzheimer’s disease

open access: yesFrontiers in Human Neuroscience, 2023
ObjectiveTo investigate the relationship between cortico-motor excitability and cognitive reserve (CR) in cognitively unimpaired older adults (CU) and in older adults with mild cognitive impairment or mild dementia due to Alzheimer’s disease (AD ...
Stephanie S. Buss   +16 more
doaj   +1 more source

THE EXCITEMENT OF DISCOVERY [PDF]

open access: yesAnnual Review of Biochemistry, 2004
I had the good luck to start research at the dawn of molecular biology when it was possible to ask fundamental questions about the nature of the nucleic acids and how information is transferred in living systems. The search for answers led me into many different areas, often with the question of how molecular structure leads to biological function ...
openaire   +2 more sources

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model

open access: yesFrontiers in Pharmacology, 2019
The cardiac Nav1.5 mediated sodium current (INa) generates the upstroke of the action potential in atrial and ventricular myocytes. Drugs that modulate this current can therefore be antiarrhythmic or proarrhythmic, which requires preclinical evaluation ...
Dieter V. Van de Sande   +7 more
doaj   +1 more source

Minimal requirements for a neuron to coregulate many properties and the implications for ion channel correlations and robustness

open access: yeseLife, 2022
Neurons regulate their excitability by adjusting their ion channel levels. Degeneracy – achieving equivalent outcomes (excitability) using different solutions (channel combinations) – facilitates this regulation by enabling a disruptive change in one ...
Jane Yang   +3 more
doaj   +1 more source

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