Results 21 to 30 of about 2,961,092 (275)
Molecular Pain, 2008 The effects of GABA, excitatory amino-acid receptors antagonists and a glial metabolism inhibitor on primary-afferent excitation in the spinal dorsal horn were studied by imaging the presynaptic excitation of high-threshold afferents in cord slices from ...
Murase Kazuyuki +2 more
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Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition
Annals of Clinical and Translational Neurology, 2020 Objective The amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) is increasingly recognized as a therapeutic target in drug‐refractory pediatric epilepsy.
Sukhvir K. Wright +9 more
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Molecular Brain, 2023 It is well documented that 17β estradiol (E2) regulates excitatory synaptic transmission at hippocampal Shaffer-collateral (SC)-CA1 synapses, via activation of the classical estrogen receptors (ERα and ERβ).
Leigh Clements +4 more
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Salsolinol facilitates glutamatergic transmission to dopamine neurons in the posterior ventral tegmental area of rats. [PDF]
PLoS ONE, 2012 Although in vivo evidence indicates that salsolinol, the condensation product of acetaldehyde and dopamine, has properties that may contribute to alcohol abuse, the underlying mechanisms have not been fully elucidated.
Guiqin Xie, Jiang-Hong Ye
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Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]
, 1975 The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J. +9 more
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Modulation of glutamate transport and receptor binding by glutamate receptor antagonists in EAE rat brain. [PDF]
PLoS ONE, 2014 The etiology of multiple sclerosis (MS) is currently unknown. However, one potential mechanism involved in the disease may be excitotoxicity. The elevation of glutamate in cerebrospinal fluid, as well as changes in the expression of glutamate receptors ...
Grzegorz Sulkowski +3 more
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EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]
, 1989 1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
Sutor, Bernd, Hablitz, John H.
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Neurobiology of Disease, 2005 Neuronal excitotoxic death results from excess stimulation by elevated levels of extracellular glutamate acting on N-methyl-d-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
Henry C. Tseng, Marc A. Dichter
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In vivo co-ordinated interactions between inhibitory systems to control glutamate mediated hippocampal excitability. [PDF]
, 2013 We present an overview of the long-term adaptation of hippocampal neurotransmission to cholinergic and GABAergic deafferentation caused by excitotoxic lesion of the medial septum.
Rodríguez Allué, Manuel José +3 more
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Plants, 2022 Most excitatory impulses received by neurons are mediated by ionotropic glutamate receptors (iGluRs). These receptors are located at the apex and play an important role in memory, neuronal development, and synaptic plasticity.
Ruphi Naz +7 more
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