Results 131 to 140 of about 408,389 (348)
Neurobiology of Disease, 2013 After 1 h of lithium-pilocarpine status epilepticus (SE), immunocytochemical labeling of NMDA receptor NR1 subunits reveals relocation of subunits from the interior to the cell surface of dentate gyrus granule cells and CA3 pyramidal cells ...
David E. Naylor +3 more
doaj
Role of Connexin 36 in Autoregulation of Oxytocin Neuronal Activity in Rat Supraoptic Nucleus
ASN Neuro, 2019 In the supraoptic nucleus (SON), the incidence of dye coupling among oxytocin (OT) neurons increases significantly in nursing mothers. However, the type(s) of connexin (Cx) involved is(are) unknown.
Ping Wang +7 more
doaj +1 more source
Epilepsia Open, 2020 Objective Ion channels belonging to subfamily A of voltage‐gated potassium channels (Kv1) are highly expressed on axons, where they play a key role in determining resting membrane potential, in shaping action potentials, and in modulating action ...
Jiaxin Du, Viktor Vegh, David C. Reutens
doaj +1 more source
Population rate coding in recurrent neuronal networks with undetermined-type neurons [PDF]
arXiv, 2019 Neural coding is a key problem in neuroscience, which can promote people's understanding of the mechanism that brain processes information. Among the classical theories of neural coding, the population rate coding has been studied widely in many works.
arxiv
The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression
Advanced Science, EarlyView.LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao +7 more
wiley +1 more source
Unsupervised learning by a nonlinear network with Hebbian excitatory and anti-Hebbian inhibitory neurons [PDF]
arXiv, 2018 This paper introduces a rate-based nonlinear neural network in which excitatory (E) neurons receive feedforward excitation from sensory (S) neurons, and inhibit each other through disynaptic pathways mediated by inhibitory (I) interneurons. Correlation-based plasticity of disynaptic inhibition serves to incompletely decorrelate E neuron activity ...
arxiv
Electric Field‐Driven Conformational Changes in Molecular Memristor and Synaptic Behavior
Advanced Science, EarlyView.Self‐assembled monolayers (SAMs) based molecular device is used for the emulation of synaptic functions. The device operates with a novel switching mechanism via incoherent charge transport, inducing conformational changes. With a low energy consumption (8.0 pJ µm−2), the system shows promise for neuromorphic computing, offering potential in low‐energy,
Chanjin Lim +8 more
wiley +1 more source
eLife, 2018 The cellular and synaptic mechanisms driving cell-type-specific function during various cortical network activities and behaviors are poorly understood.
Aurélie Pala, Carl CH Petersen
doaj +1 more source
Advanced Science, EarlyView.This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu +9 more
wiley +1 more source
Neural computation at the thermal limit [PDF]
arXiv, 2014 Although several measurements and analyses support the idea that the brain is energy-optimized, there is one disturbing, contradictory observation: In theory, computation limited by thermal noise can occur as cheaply as ~$2.9\cdot 10^{-21}$ joules per bit (kTln2).
arxiv