Results 151 to 160 of about 363,862 (308)

High Linearity and Symmetry Ferroelectric Artificial Neuromorphic Devices Based on Ultrathin Indium‐Tin‐Oxide Channels

Advanced Electronic Materials, EarlyView.
Ultrathin ITO and ferroelectric HZO are used to fabricate synaptic transistors. The device has a great on/off ratio ≈108 with a memory window of 1.73 V, successfully simulates the characteristics of the human brain, and achieves good linearity of 0.45 for potential and 0.73 for depression and low asymmetry of 0.89.
Siwei Wang, Xuemeng Hu, Baifan Qian, Jiajie Yu, Zhenhai Li, Qingqing Sun, David Wei Zhang, Qingxuan Li, Lin Chen   +8 more
wiley   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

Aggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang, Chengyuan Qian, Yuncong Chen, Weijiang He, Zijian Guo   +4 more
wiley   +1 more source

Effects of Qingyangshen glycosides on neuroplasticity in a mouse model of social defeat

Animal Models and Experimental Medicine, EarlyView.
Summary of the experimental effects of qingyangshen glycosides on neuroplasticity in mice model of social defeat. Abstract Background Qingyangshen (Cynanchum otophyllum C.K. Schneid) is a folk drug for treating depression and other mental disorders induced by social defeat stress.
Jingru Wang, Weishi Chen, Qiang Zhu, Yao Liu, Zheng Kang, Dingding Liu, Guirong Zeng   +6 more
wiley   +1 more source

Flexible optoelectronic neural transistors with broadband spectrum sensing and instant electrical processing for multimodal neuromorphic computing

SmartMat, Volume 4, Issue 2, April 2023., 2023
Integration of multimode signal (e.g., optical and electrical) sensing and processing functions into a single neuromorphic device has become an important trend. Here, a flexible optoelectronic neural transistor with the channel region consisting of a one‐step spin‐coated tri‐blend film composed of 2,7dioctyl[1]benzothieno[3,2‐b][1]benzothiophene (C8 ...
Yao Ni, Lu Yang, Jiulong Feng, Jiaqi Liu, Lin Sun, Wentao Xu   +5 more
wiley   +1 more source

Synaptic sampling: A connection between PSP variability and uncertainty explains neurophysiological observations [PDF]

arXiv, 2015
When an action potential is transmitted to a postsynaptic neuron, a small change in the postsynaptic neuron's membrane potential occurs. These small changes, known as a postsynaptic potentials (PSPs), are highly variable, and current models assume that this variability is corrupting noise.
arxiv  

Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model

Animal Models and Experimental Medicine, EarlyView.
Our study used behavioral tests, laser speckle flowmetry, long‐term potentiation, histochemical staining, molecular experiments, and voxel‐based morphometry to evaluate the hippocampal impairments. It demonstrates early functional and structural impairments in the hippocampus contributing to learning and memory deficits after 1 month of BCAS ...
Ping Tang, Yi Sun, Chunsheng Yang, Nan Zhang   +3 more
wiley   +1 more source

Recent advances in 2D organic−inorganic heterostructures for electronics and optoelectronics

SmartMat, Volume 4, Issue 2, April 2023., 2023
The integration of atomically‐thin 2D inorganic materials with large numbers of available organic materials can create exciting new opportunities for future multifunctional devices. This review summarizes the recent advances in 2D organic−inorganic‐based heterostructures, including their structures, properties, synthesis, and applications in electronic
Jahangir Khan, Rana Tariq Mehmood Ahmad, Junyang Tan, Rongjie Zhang, Usman Khan, Bilu Liu   +5 more
wiley   +1 more source

Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain

Animal Models and Experimental Medicine, EarlyView.
The electrophysiological change in neurons might contribute to the cognitive and emotional changes during pregnancy. Abstract Background Pregnancy affects learning and memory in women. Thus, to investigate the effects of pregnancy, the authors examined the brain electrophysiology of pregnant mice.
Xuefan Bin, Huijuan Luo
wiley   +1 more source

Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship

Annals of Neurology, EarlyView.
Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.
Ugo Sorrentino, Audrey G. O'Neill, Justin M. Kollman, Hyder A. Jinnah, Michael Zech   +4 more
wiley   +1 more source

Visual and auditory attention in individuals with DYRK1A and SCN2A disruptive variants

Autism Research, EarlyView.
Abstract This preliminary study sought to assess biomarkers of attention using electroencephalography (EEG) and eye tracking in two ultra‐rare monogenic populations associated with autism spectrum disorder (ASD). Relative to idiopathic ASD (n = 12) and neurotypical comparison (n = 49) groups, divergent attention profiles were observed for the monogenic
Caitlin M. Hudac, Kelsey Dommer, Monique Mahony, Trent D. DesChamps, Brianna Cairney, Rachel Earl, Evangeline C. Kurtz‐Nelson, Jessica Bradshaw, Raphael A. Bernier, Evan E. Eichler, Emily Neuhaus, Sara Jane Webb, Frederick Shic   +12 more
wiley   +1 more source