Results 161 to 170 of about 141,800 (341)
Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin +10 more
wiley +1 more source
The Enteric Nervous System (ENS) plays a key role in regulating the function of the gastrointestinal tract. The knowledge about the function of neurons is based on experiments using the intracellular recording method.
Michał Ceregrzyn +2 more
doaj
TRPC3 Underlies GABAB Receptor-Mediated Augmentation of Type-1 Metabotropic Glutamate Receptor-Coupled Slow Excitatory Postsynaptic Potential in Cerebellar Purkinje Neurons [PDF]
Jinbin Tian, Michael X. Zhu
openalex +1 more source
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh +10 more
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Schaffer-Specific Local Field Potentials Reflect Discrete Excitatory Events at Gamma Frequency That May Fire Postsynaptic Hippocampal CA1 Units [PDF]
Antonio Fernández‐Ruiz +3 more
openalex +1 more source
Absence seizures: Update on signaling mechanisms and networks
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Mechanistic explanation of neuroplasticity using equivalent circuits. [PDF]
Nilsson MNP.
europepmc +1 more source

