Results 171 to 180 of about 408,389 (348)

The neuropharmacology of baclofen [PDF]

open access: yes, 1988
AI Shapovalov   +104 more
core   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang   +9 more
wiley   +1 more source

Inhibition of Acute mGluR5-Dependent Depression in Hippocampal CA1 by High-Frequency Magnetic Stimulation

open access: yesBrain Sciences
High-frequency magnetic stimulation (HFMS) applied directly to the hippocampal slice preparation in vitro induces activity-dependent synaptic plasticity and metaplasticity.
Norman Holl   +4 more
doaj   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Next‐Generation Flexible and Stretchable Vision Systems for Advanced Image Acquisition and Processing

open access: yesFlexTech, EarlyView.
ABSTRACT Robotic vision is essential for enabling intelligent and autonomous systems across diverse applications, including manufacturing, healthcare, autonomous navigation, and surveillance. However, conventional vision systems, which rely on rigid imaging hardware, face challenges such as limited adaptability, high energy consumption, and processing ...
Jinhong Park   +4 more
wiley   +1 more source

Intelligent flexible memristors for artificial synapses and neuromorphic computing

open access: yesFlexMat, EarlyView.
Abstract Memristors have garnered significant attention in the field of non‐volatile memory devices due to their excellent characteristics such as miniaturization, low power consumption, high performance, and non‐volatility. Particularly with the development of flexible electronics in recent years, flexible memristors have shown immense potential in ...
Qingyao Mao   +3 more
wiley   +1 more source

Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine

open access: yesGlia, EarlyView.
Astroglial CB1R mediates long‐term synaptic plasticity (LTD) in the Nucleus accumbens. Amphetamine saturates adenosine receptors and blocks LTD in males, but not females. Locomotor effects of amphetamine require astroglial CB1R in males, but not in females.
Yamuna Mariani   +15 more
wiley   +1 more source

Subtle Alterations in Hippocampal Neuronal Activity Coincide With Early Sex‐Specific Differences in Amyloidosis and Microglia in a Pre‐Symptomatic Mouse Model of Alzheimer‐Like Pathology

open access: yesGlia, EarlyView.
In a pre‐symptomatic mouse model of Alzheimer disease, despite higher amyloid‐β load, females display fewer plaques than males. More efficient synaptic transmission as well as less microgliosis point to better early coping with pathogenesis in females.
Thomas Chaigneau   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy