Results 171 to 180 of about 408,389 (348)
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann+2 more
wiley +1 more source
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang+9 more
wiley +1 more source
High-frequency magnetic stimulation (HFMS) applied directly to the hippocampal slice preparation in vitro induces activity-dependent synaptic plasticity and metaplasticity.
Norman Holl+4 more
doaj +1 more source
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang+4 more
wiley +1 more source
ABSTRACT Robotic vision is essential for enabling intelligent and autonomous systems across diverse applications, including manufacturing, healthcare, autonomous navigation, and surveillance. However, conventional vision systems, which rely on rigid imaging hardware, face challenges such as limited adaptability, high energy consumption, and processing ...
Jinhong Park+4 more
wiley +1 more source
Intelligent flexible memristors for artificial synapses and neuromorphic computing
Abstract Memristors have garnered significant attention in the field of non‐volatile memory devices due to their excellent characteristics such as miniaturization, low power consumption, high performance, and non‐volatility. Particularly with the development of flexible electronics in recent years, flexible memristors have shown immense potential in ...
Qingyao Mao+3 more
wiley +1 more source
Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine
Astroglial CB1R mediates long‐term synaptic plasticity (LTD) in the Nucleus accumbens. Amphetamine saturates adenosine receptors and blocks LTD in males, but not females. Locomotor effects of amphetamine require astroglial CB1R in males, but not in females.
Yamuna Mariani+15 more
wiley +1 more source
In a pre‐symptomatic mouse model of Alzheimer disease, despite higher amyloid‐β load, females display fewer plaques than males. More efficient synaptic transmission as well as less microgliosis point to better early coping with pathogenesis in females.
Thomas Chaigneau+7 more
wiley +1 more source