Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]
, 2019 FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran +14 more
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Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity. [PDF]
, 2018 The morphology and function of neuronal synapses are regulated by neural activity, as manifested in activity-dependent synapse maturation and various forms of synaptic plasticity.
Bi, Guo-Qiang +4 more
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Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus
Brain Stimulation, 2022 Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
doaj
Journal of Biomedical Science, 2017 Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits ...
Hui Ye, Stephanie Kaszuba
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Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]
, 2017 The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
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Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons [PDF]
Proceedings of the National Academy of Sciences, 1998 The manner in which the thousands of synaptic inputs received by a pyramidal neuron are summed is critical both to our understanding of the computations that may be performed by single neurons and of the codes used by neurons to transmit information. Recent work on pyramidal cell dendrites has shown that subthreshold synaptic inputs are modulated by ...
Nathaniel N. Urban, Germán Barrionuevo
openalex +4 more sources
γ-Hydroxybutyrate inhibits excitatory postsynaptic potentials in rat hippocampal slices
European Journal of Pharmacology, 1999 Gamma-Hydroxybutyrate (GHB) has been shown to mimic different central actions of ethanol, to suppress alcohol withdrawal syndrome, and to reduce alcohol consumption both in rats and in humans. The aim of the present study was to determine if GHB shared with alcohol the ability to inhibit glutamate action at both NMDA and AMPA/kainate receptors.
BERTON, FULVIA +6 more
openaire +5 more sources
Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction. [PDF]
PLoS ONE, 2014 Members of the TGF-β superfamily play numerous roles in nervous system development and function. In Drosophila, retrograde BMP signaling at the neuromuscular junction (NMJ) is required presynaptically for proper synapse growth and neurotransmitter ...
Myung-Jun Kim, Michael B O'Connor
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Gamma rhythms and beta rhythms have different synchronization properties [PDF]
, 2000 Experimental and modeling efforts suggest that rhythms in the CA1 region of the hippocampus that are in the beta range (12-29 Hz) have a different dynamical structure than that of gamma (30-70 Hz).
Ermentrout, G.B. +3 more
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Alterations in brain connectivity due to plasticity and synaptic delay
, 2017 Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronisation in a ...
Batista, A. M. +8 more
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