Cortical Stimulation Induces Excitatory Postsynaptic Potentials of Inferior Colliculus Neurons in a Frequency-Specific Manner. [PDF]
Front Neural Circuits, 2020 Corticofugal modulation of auditory responses in subcortical nuclei has been extensively studied whereas corticofugal synaptic transmission must still be characterized.
Qi J +5 more
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A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis. [PDF]
Sci Rep, 2022 The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis and to neuronal cell death in models of excitotoxicity and traumatic ...
Fearey BC +7 more
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The inhibition of evoked excitatory postsynaptic potentials produced by ammonium chloride in rat hippocampal CA1 neurons. [PDF]
Heliyon, 2020 The depression of evoked fast excitatory postsynaptic potentials (EPSPs) following superfusion with various concentrations (3 μM-5 mM) of ammonium chloride (NH4Cl) were investigated in rat hippocampal CA1 neurons.
Kameyama N, Murai Y, Tanaka E.
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Postsynaptic spiking determines anti-Hebbian LTD in visual cortex basket cells. [PDF]
Front Synaptic NeurosciLong-term plasticity at pyramidal cell to basket cell (PC → BC) synapses is important for the functioning of cortical microcircuits. It is well known that at neocortical PC → PC synapses, dendritic calcium (Ca2+) dynamics signal coincident pre-and ...
Chou CYC +6 more
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Imperfect space clamp permits electrotonic interactions between inhibitory and excitatory synaptic conductances, distorting voltage clamp recordings. [PDF]
PLoS ONE, 2011 The voltage clamp technique is frequently used to examine the strength and composition of synaptic input to neurons. Even accounting for imperfect voltage control of the entire cell membrane ("space clamp"), it is often assumed that currents measured at ...
Alon Poleg-Polsky, Jeffrey S Diamond
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Impact of the activation rate of the hyperpolarization-activated current $I_{\rm h}$ on the neuronal membrane time constant and synaptic potential duration [PDF]
Eur. Phys. J. Spec. Top. (2021), 2021 The temporal dynamics of membrane voltage changes in neurons is controlled by ionic currents. These currents are characterized by two main properties: conductance and kinetics. The hyperpolarization-activated current ($I_{\rm h}$) strongly modulates subthreshold potential changes by shortening the excitatory postsynaptic potentials and decreasing their
arxiv +1 more source
Regulation of spike timing-dependent plasticity of olfactory inputs in mitral cells in the rat olfactory bulb. [PDF]
PLoS ONE, 2012 The recent history of activity input onto granule cells (GCs) in the main olfactory bulb can affect the strength of lateral inhibition, which functions to generate contrast enhancement.
Teng-Fei Ma +7 more
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Disinhibition mediates a form of hippocampal long-term potentiation in area CA1. [PDF]
PLoS ONE, 2009 The hippocampus plays a central role in memory formation in the mammalian brain. Its ability to encode information is thought to depend on the plasticity of synaptic connections between neurons.
Jake Ormond, Melanie A Woodin
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Hyperpolarization following activation of K+ channels by excitatory postsynaptic potentials [PDF]
Nature, 1983 We have postulated that an excitatory postsynaptic potential (e.p.s.p.) may open voltage-sensitive K+ ('M') channels, in an appropriate depolarizing range, and that this could alter the e.p.s.p. waveform. Consequently, the fast e.p.s.p. in neurones of sympathetic ganglia, elicited by a nicotinic action of acetylcholine (ACh), could be followed by a ...
Tsuneo Tosaka +3 more
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Frontiers in Pharmacology, 2021 Extracts of the tropical Cinderella plant Synedrella nodiflora are used traditionally to manage convulsive conditions in the West African sub-region.
Patrick Amoateng +8 more
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