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Pentobarbital: Selective Depression of Excitatory Postsynaptic Potentials

Science, 1973
The effects of pentobarbital (Nembutal) on synaptic transmission and postsynaptic potentials were studied by the use of several invertebrate preparations. Pentobarbital selectively and reversibly depressed both excitatory postsynaptic potentials and sodium-dependent postsynaptic responses to putative excitatory transmitters without affecting either ...
J L, Barker, H, Gainer
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Stretch-evoked excitatory postsynaptic potentials in motoneurons

Brain Research, 1971
Abstract The profile of excitatory postsynaptic potential (EPSP) produced on triceps surae motoneurons by 5 msec duration triangular wave stretch of de-efferented medial gastrocnemius (MG) and soleus (S) muscles was observed on anesthetized, spinalized cats.
D G, Stuart, W D, Willis, R M, Reinking
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Principal component analysis of minimal excitatory postsynaptic potentials

Journal of Neuroscience Methods, 1998
'Minimal' excitatory postsynaptic potentials (EPSPs) are often recorded from central neurones, specifically for quantal analysis. However the EPSPs may emerge from activation of several fibres or transmission sites so that formal quantal analysis may give false results.
A V, Astrelin   +4 more
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Unitary Excitatory Postsynaptic Potentials in Clarke's Column Neurones

Nature, 1967
IT is generally believed that synaptic transmission is effected by a quantal release of transmitter substances, such as has been demonstrated for the neuromuscular junction1. The quantal nature of synaptic transmission in the central nervous system is more difficult to investigate, one reason being that many presynaptic fibres usually contribute to the
E, Eide   +4 more
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Summation of excitatory postsynaptic potentials in hippocampal pyramidal cells

Journal of Neurophysiology, 1983
The summation of excitatory postsynaptic potentials (EPSPs) generated in separate parts of the dendritic tree of hippocampal pyramidal cells has been investigated using the in vitro slice preparation. Two separate inputs with known synaptic location were used.
I A, Langmoen, P, Andersen
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Summation of excitatory postsynaptic potentials in electrically-coupled neurones

Neuroscience, 2009
Dendritic electrical coupling increases the number of effective synaptic inputs onto neurones by allowing the direct spread of synaptic potentials from one neurone to another. Here we studied the summation of excitatory postsynaptic potentials (EPSPs) produced locally and arriving from the coupled neurone (transjunctional) in pairs of electrically ...
Y, Vazquez   +3 more
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Nicotinic cholinoceptor-mediated excitatory postsynaptic potentials in rat nucleus ambiguus

Experimental Brain Research, 1993
In rat brainstem slice preparations, intracellular recording from neurons (n = 39) in the compact formation of the nucleus ambiguus (AMBc) revealed spontaneous and miniature excitatory postsynaptic potentials (EPSPs; n = 11) that, along with acetylcholine-induced depolarization, were enhanced by physostigmine (10 microM; n = 2) and blocked by dihydro ...
M, Zhang   +4 more
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Ghrelin Potentiates Miniature Excitatory Postsynaptic Currents in Supraoptic Magnocellular Neurones

Journal of Neuroendocrinology, 2009
Ghrelin is an orexigenic peptide discovered in the stomach as a ligand of the orphan G‐protein coupled receptor, and participates in the regulation of growth hormone (GH) release. Previous studies have demonstrated that ghrelin suppressed water intake and stimulated the secretion of arginine vasopressin in rats. We examined the effect of ghrelin on the
T, Yokoyama   +8 more
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Voltage dependence of excitatory postsynaptic potentials of rat neocortical neurons

Journal of Neurophysiology, 1991
1. The properties of excitatory postsynaptic potentials (EPSPs) of rat neocortical neurons were investigated with a fast single-electrode current-voltage clamp in vitro. Typically, apparently pure EPSPs were obtained by selection of electric stimuli of low intensity. 2.
Deisz, R.   +2 more
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Effect of glutamate receptor antagonists on excitatory postsynaptic potentials in striatum

Brain Research Bulletin, 1998
Glutamate, as the main transmitter of corticostriatal pathway, has a crucial role in the regulation of the activity of striatal cells as well as in pathogenesis of some diseases characterized by striatal malfunction caused by overexcitation of neurons. In the present study, the role of ionotropic excitatory amino acid receptors was investigated in the ...
I, Világi   +3 more
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