Results 211 to 220 of about 76,705 (331)

Oxidative Glutamate Toxicity Can Be a Component of the Excitotoxicity Cascade [PDF]

, 2001
D Schubert, Dana Piasecki
openalex   +1 more source

Editorial: Environmental clues to brain disease

Frontiers in Aging Neuroscience, 2023
Patrizia Giannoni, Federica Bertaso, Gustavo Provensi   +2 more
doaj   +1 more source

Memantine Exacerbates Trimethyltin‐Induced Neurodegeneration and Delays Cognitive Impairment Recovery

Neuropsychopharmacology Reports, Volume 45, Issue 2, June 2025.
Trimethyltin (TMT) induces transient neuronal loss and cognitive impairments, serving as a model for transient brain damage. This study investigated the effects of early memantine (MEM) treatment on TMT‐induced brain injury. Memantine worsened TMT‐induced cognitive impairment and neuronal degeneration in the hippocampus, suggesting that early MEM ...
Yusuke Onaka, Taro Yamaguchi, Takumu Yamasaki, Koki Morishige, Masanori Yoneyama   +4 more
wiley   +1 more source

Neuronal STING activation mediates inflammation-induced neurodegeneration via ferroptosis pathways in multiple sclerosis. [PDF]

Biophys Rep
Wang W, Guo M, Tu X, Jiang M, Zhang CJ.
europepmc   +1 more source

Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain [PDF]

, 2001
Vincent Laudenbach, Girolamo Calò, Remo Guerrini, G Lamboley, Jean‐François Benoist, Philippe Evrard, Pierre Gressèns   +6 more
openalex   +1 more source

Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background L‐asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose‐limiting complications and compromised event‐free survival. Procedure This study conducted a genome‐wide association study (GWAS) in a discovery cohort of
Spencer J. Anderson, Erika N. Scott, Edward J. Raack, Wan‐Chun Chang, Miguel Córdova‐Delgado, Jessica N. Trueman, Catrina M. Loucks, S. Rod. Rassekh, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety (CPNDS) consortium   +10 more
wiley   +1 more source

Fucoxanthin Inhibits the NMDA and AMPA Receptors Through Regulating the Calcium Response on Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Juvenile Mice. [PDF]

Neural Plast
Le NHT, Park SA, Kim YM, Ahn DK, Jung W, Han SK.   +5 more
europepmc   +1 more source

Neuroprotection by Δ⁹-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-InducedIn VivoExcitotoxicity [PDF]

, 2001
Mario van der Stelt, Wouter B. Veldhuis, P.R. Bär, Gerrit A. Veldink, Johannes F.G. Vliegenthart, Klaas Nicolay   +5 more
openalex   +1 more source

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, Volume 6, Issue 5, May 2025.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

The Possible Role of Metformin and Fibroblast Growth Factor-21 in Multiple Sclerosis Neuropathology: Birds of a Feather Flock Together. [PDF]

Eur J Neurosci
Abulaban AA, Al-Kuraishy HM, Al-Gareeb AI, Ahmed EA, Alruwaili M, Alexiou A, Papadakis M, El-Saber Batiha G.   +7 more
europepmc   +1 more source