Results 201 to 210 of about 80,747 (355)

Inhibition of Bcl-xL prevents pro-death actions of ΔN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity [PDF]

, 2017
Hana Park, Pawel Licznerski, Nelli Mnatsakanyan, Yulong Niu, Silvio Sacchetti, Jing Wu, Brian M. Polster, Kambiz N. Alavian, Elizabeth A. Jonas   +8 more
openalex   +1 more source

Progress of Immunotherapies in Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Parkinson's disease (PD) is caused by an immune disorder triggered by α‐synuclein, leading to a persistent neuroinflammatory cycle that drives the disease from non‐motor symptoms to the motor stage. Second, it presents active and passive immunotherapy strategies targeting α‐synuclein and their potential in slowing down the disease progression.
Yong Peng, Xu‐hui Kang, Shun‐yu Yao, Xiuli Zhang, Sugimoto Kazuo, Jia Liu, Miao‐qiao Du, Lan‐xin Lin, Dai‐yi Jiang, Quan Chen, Hong Jin   +10 more
wiley   +1 more source

Magnesium neuroprotection in retinal ganglion cells: A computational study of frequency-dependent therapeutic windows and intervention timing. [PDF]

PLoS One
Borjkhani M, Borjkhani H, Sharif MA.
europepmc   +1 more source

Pharmacokinetics and Neuroprotective Efficacy of Poly‐Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The R18D peptide exhibits a favorable pharmacokinetic profile and significantly reduces infarct volume in a rat model of middle cerebral artery occlusion (MCAO) followed by reperfusion. These findings highlight the potential clinical utility of R18D as a neuroprotective therapy for stroke patients undergoing endovascular recanalization interventions ...
Bruno P. Meloni, Stuart K. Gribble, Meghan G. Thomas, Ayelet Weksler, Lena Finkelstein, Lena Fishtein, Dimitry Kovalchuk, Gilad Maximov, Avital Schauder, Keren Kigel‐Zur, Sigal Meilin   +10 more
wiley   +1 more source

Effect of Fucoxanthin on Mitochondrial Function During Excitotoxicity

Electronic Thesis or DissertationMitochondria are essential for neuronal function due to their critical role in cellular energy metabolism. Mitochondrial dysfunction is a central pathological process during excitotoxicity, contributing to overproduction ...
Ferdous, Khondoker Adeba
core  

α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionate Receptor Subunit Composition and cAMP-response Element-binding Protein Regulate Oligodendrocyte Excitotoxicity

, 2006
Wenbin Deng, Rachael L. Neve, Paul A. Rosenberg, Joseph J. Volpe, Frances E. Jensen   +4 more
openalex   +1 more source

Quinazoline-based tricyclic compounds that regulate programmed cell death, induce neuronal differentiation, and are curative in animal models for excitotoxicity and hereditary brain disease [PDF]

, 2015
Alex Vainshtein, L. Veenman, Alexander Shterenberg, Sukhdev Singh, Ahmad Masarwa, Bibek Dutta, Biana Island, Einav Tsoglin, Evgeny Levin, Svetlana Leschiner, Inbal Maniv, Liron Pe'er, Irina Otradnov, Salman Zubedat, Shlomit Aga‐Mizrachi, Abraham Weizman, Avi Avital, Ilan Marek, Moshe Gavish   +18 more
openalex   +1 more source

Fractional anisotropy from diffusion tensor imaging correlates with acute astrocyte and myelin swelling in neonatal swine models of excitotoxic and hypoxic‐ischemic brain injury

, 2021
Jennifer K. Lee, Dapeng Liu, Dengrong Jiang, Ewa Kulikowicz, Aylin Tekes, Peiying Liu, Qin Qin, Raymond C. Koehler, Manisha Aggarwal, Jiangyang Zhang, Lee J. Martin   +10 more
openalex   +2 more sources

Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress.

Toxicology, 2017
Daiane Cattani, P. Cesconetto, Mauren K Tavares, E. B. Parisotto, P. A. de Oliveira, Carla Elise Heinz Rieg, M. Leite, R. Prediger, N. Wendt, Guilherme Razzera, D. W. Filho, A. Zamoner   +11 more
semanticscholar   +1 more source

Relationship between hTERT levels and oxidative stress in epilepsy patients

Epilepsia Open, Volume 11, Issue 3, Page 752-763, June 2026.
Abstract Objective Human telomerase reverse transcriptase (hTERT) is a key determinant of telomere maintenance and cellular aging. Oxidative stress plays a role in neurodegenerative processes by causing cellular damage through increased reactive oxygen species.
Muhammed Mehdi Üremiş, Deniz Tuncel Berktaş, Nuray Üremiş, Fatma İnanç Tolun   +3 more
wiley   +1 more source