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SIRT4 prevents excitotoxicity via modulating glutamate metabolism in glioma cells
Excitotoxicity is the presence of excessive glutamate, which is normally taken up by glutamate transporters on astrocytes. Glutamate transporter 1 (GLT-1) is the major transporter on glia cells clearing more than 90% of the glutamate.
Gizem Donmez Yalcin
exaly +2 more sources
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Microglia activation contributes to quinolinic acid-induced neuronal excitotoxicity through TNF-α
Apoptosis: an International Journal on Programmed Cell Death, 2017Zheng-Hong Qin, Rong Han
exaly
N-methyl-D-aspartate Receptor Subtypes: Multiple Roles in Excitotoxicity and Neurological Disease
Neuroscientist, 2005David R Lynch
exaly
The Role of Excitotoxicity in Neurodegenerative Disease
Pharmacology & Therapeutics, 1999Adam Doble
exaly

