Results 171 to 180 of about 80,747 (355)
Factors in glutamate excitotoxicity, inflammation and epilepsy
, 2012 Studying the mechanisms underlying glutamate excitotoxicity and inflammatory responses provides hints to the pathology of neurological diseases such as epilepsy.
Zhu, Shanshan
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Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Role of excitotoxicity in the degeneration of motor neurones in ALS
, 2005 Massimo Tortarolo
openalex +1 more source
Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons [PDF]
, 2006 Hisashi Shirakawa +4 more
openalex +1 more source
ChemBioChem, Volume 27, Issue 11, 15 June 2026.This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle +6 more
wiley +1 more source
, 2018 1 Broadside. 48"W x 36"HNeurodegenerative diseases are characterized by neuronal impairment or death Glutamate excitotoxicity is a neuronal death pathway involved in many neurodegenerative diseases1 Glutamate excitotoxicity occurs when extracellular
Keramidas, Christina
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Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
, 2017 34 p.Neurodegenerative diseases affecting the central nervous system are characterized by neuronal impairment or death. One mechanism leading to neuronal death in many neurodegenerative diseases is glutamate excitotoxicity.
Keramidas, Christina
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