Results 151 to 160 of about 12,017 (197)

Monitoring Reactive Oxygen Species‐Induced Cellular Responses in Retinal Pigment Epithelium Cells Using Autofluorescence Multispectral Imaging

Advanced Photonics Research, Volume 7, Issue 10, October 2026.
Autofluorescence multispectral imaging enables label‐free assessment of oxidative stress in retinal pigment epithelial cells by capturing stressor‐specific metabolic signatures. Distinct autofluorescence patterns and redox changes allow classification of cellular stress states across multiple pathways.
Abhilash Goud Marupally, Aline Knab, Ayad G. Anwer, Yuan Tian, Shannon Handley, Abbas Habibalahi, Andrew White, Nicole Carnt, Robert Casson, Ewa M. Goldys   +9 more
wiley   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, Volume 13, Issue 56, 9 October 2026.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

Mitochondrial fusion and fission is a dynamic process critical for the maintenance of mitochondrial function and cell viability. During excitotoxicity neuronal mitochondria are fragmented but the mechanism underlying this process is poorly understood ...
Olloquequi González, Jordi, Puyal, Julien, Segarra-Mondejar, Marc, Muñoz, Juan Pablo, Zorzano Olarte, Antonio, Soriano Zaragoza, Francesc X. (Francesc Xavier), Pérez Clausell, Jeús, Martorell-Riera, Alejandro, Ginet, Vanessa, Palacín Prieto, Manuel, Reina del Pozo, Manuel   +10 more
core  

Structural compression and entorhinal vulnerability: Linking tentorial adjacency to tau burden and dementia progression

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Early neurofibrillary tau degeneration in the entorhinal cortex (EC) is a hallmark of Alzheimer's disease (AD) and aging. We propose a biomechanical cascade hypothesis, suggesting proximity to the tentorial incisura (TI) may render the EC susceptible to chronic mechanical stress, potentially contributing to tau pathology.
Luyue Zhang, Ana M. Franceschi, John F. Crary, Frank A. Provenzano, for the Alzheimer's Disease Neuroimaging Initiative   +4 more
wiley   +1 more source

Neuroprotection after transient middle cerebral artery occlusion in male rats using kojic acid nanostructured lipid carriers: A behavioral, biochemical, and histological study on hippocampal CA1 region

Animal Models and Experimental Medicine, Volume 9, Issue 10, Page 2075-2088, October 2026.
This study demonstrates that kojic acid–loaded nanostructured lipid carriers (KA‐NLC) provide significant neuroprotection in a male rat model of middle cerebral artery occlusion (MCAO)–induced stroke. Treatment with KA‐NLCs reduced cerebral edema, improved motor and coordination balance and neurological scores, and enhanced spatial and avoidance memory.
Mobina Gheibi, Erfan Ghadirzadeh, Javid Tebyani, Seyedeh Mohadeseh Moyaedi, Khadijeh Khezri, Majid Saeedi, Ali Siahposht‐Khachaki, Narges Karimi, Melika Pourhossein, Shiva Shadi, Sasan Shafiei, Atena Sharifi‐Razavi   +11 more
wiley   +1 more source

Ensemble‐Based Machine Learning Models for Classifying Intervention‐Related Psychological Outcome Patterns in Menopausal Women Treated With Pimpinella anisum

Brain and Behavior, Volume 16, Issue 10, October 2026.
This study develops an ensemble‐based machine learning approach to detect and predict psychological disorders in menopausal women using clinical and questionnaire data. Random Forest achieved the best performance. The framework supports early risk identification and integrates statistical validation with Unani‐based and home remedy interventions to ...
Md Belal Bin Heyat, Arshiya Sultana, Attiq Ur Rehman, Arfa Begum, Mohamad Sawan   +4 more
wiley   +1 more source

Blood Flow Restriction Training in Stroke Rehabilitation: A Narrative Review of Current Evidence and Future Directions

Brain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Background Post‐stroke motor deficits cause disability, while paresis and comorbidities may limit high‐intensity training. Blood flow restriction training (BFRT) combines low‐intensity exercise with partial vascular occlusion and may promote neuromuscular adaptations at low loads.
Jiawei Tong, Lei Song, Juan Jin, Fangfang Li, Tao Huang, Hang Ying, Jiawei Zhu, Jue Wang, Jie Zhuang   +8 more
wiley   +1 more source

Phytochemistry, Pharmacological Potential, and Future Prospects of Abietane‐Type Diterpenoids From Salvia rosmarinus

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The review delves into the findings on abietane diterpenes from Salvia rosmarinus. It comprises the phytochemistry, biological activities, biosynthesis, degradation studies, semisynthesis, and pharmacokinetic studies of these compounds. The potential of these compounds for future development has also been highlighted.
Rida Siddiqui, Vipin Singh, Kapil Dev
wiley   +1 more source

Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco, Danillo Alencar‐Coutinho, Ana Carolina Ferreira‐Scatone, Stella Diogo‐Cavassana, Jeanne Oiticica, Karina Lezirovitz, Ricardo Ferreira Bento   +6 more
wiley   +1 more source

Progressive Cognitive Decline and Pyramidal Signs in a Patient With a Novel Homozygous c.395A>T; p.Lys132Met Mutation in CHCHD2

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Biallelic CHCHD2 variants are rare. We report a consanguineous man with a novel homozygous CHCHD2 c.395A>T (p.Lys132Met) variant who developed progressive cognitive decline, apraxia, oculomotor impairment, and pyramidal signs without parkinsonism.
Mehri Salari, Arash Soltani, Masoud Etemadifar, Kamran Rezaei   +3 more
wiley   +1 more source