Results 141 to 150 of about 12,017 (197)
Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
Analysis &Sensing, Volume 6, Issue 6, November 2026.The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 6, November 2026.ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan +3 more
wiley +1 more source
Glia, Volume 74, Issue 11, November 2026.Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton +6 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 11, Page 4099-4111, November 2026.ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac +2 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.Exposure to arsenic trioxide (As2O3) in humans is associated with dose‐dependent cortical neurodegeneration with convergent pathological mechanisms. Low and medium dose exposure induces adaptive autophagy via PI3K/AKT/mTOR suppression and high dose exposure leads to mTOR hyperactivation, autophagic failure, microglial neuroinflammation and excitotoxic ...
Prathyusha Koyya +2 more
wiley +1 more source
The Role of Astrocytes in the Inflammatory Response in Neurodiseases
MedComm, Volume 7, Issue 11, November 2026.Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng +3 more
wiley +1 more source
MedComm, Volume 7, Issue 11, November 2026.Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Multiple Sclerosis and Viruses: « Liaisons Dangereuses »
Reviews in Medical Virology, Volume 36, Issue 6, November 2026.ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina +11 more
wiley +1 more source
Environmental Toxicology, Volume 41, Issue 11, Page 1188-1200, November 2026.ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco +6 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu +5 more
wiley +1 more source