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Wernicke’s encephalopathy: an excitotoxicity hypothesis
Metabolic Brain Disease, 1997 Thiamine deficiency is a recognized cause of Wernicke's encephalopathy (WE), a condition in which small necrotic lesions are found in close proximity to the third and fourth ventricles and the Sylvian aqueduct. Although the neuropathology of WE is well-established, the pathogenic mechanisms that determine the formation and distribution of brain lesions openaire +2 more sourcesExcitotoxicity
2010 Bart Ellenbroek, Alfonso Abizaid, Shimon Amir, Martina de Zwaan, Sarah Parylak, Pietro Cottone, Eric P. Zorrilla, Lawrence H. Price, Ben J. Harrison, Christos Pantelis, Lawrence H. Price, Sophie Tambour, John C. Crabbe, Ian P. Stolerman, Nicola Simola, Micaela Morelli, Michael H. Bloch, Sarah Morgan, Angus Mackay, Gary Remington, Sidney H. Kennedy, Sakina J. Rizvi, Giovanni Hernandez, Peter Shizgal, Mitul A. Mehta, Ennio Esposito, Roberto William Invernizzi, Darren R. Christensen, Warren K. Bickel, Lynette C. Daws, Anne M. Andrews, Greg A. Gerhardt, Lawrence H. Price, Mischa de Rover, Sander Nieuwenhuis, Peter H. Boeijinga, Victoria L. Harvey, Anthony H. Dickenson, Peter Verheart, Per Svenningsson, Per E. Andrén, Antonio Pádua Carobrez, Grasielle C. Kincheski, Leandro J. Bertoglio, Kim Wolff, Iván Izquierdo, Lia Rejane M. Bevilaqua, Martin Cammarota, David H. Zald, Oliver Stiedl, Sven Ove Ögren, Joseph Zohar, Alan J. Budney, Oliver Stiedl, Sven Ove Ögren, Cecilia J. Hillard, Alfonso Abizaid, Shimon Amir, Josee E. Leysen, Samuel B. Hutton, Michael M. Morgan, MacDonald J. Christie, Paul Willner, Michael M. Morgan, MacDonald J. Christie, Martina de Zwaan, Jason C. G. Halford, Peter Riederer, Siegfried Hoyer, Francis C. Colpaert, Michael M. Morgan, MacDonald J. Christie, Michael M. Morgan, MacDonald J. Christie, Daniel Hoyer, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Kim Wolff, Mary E. Cain, Michael T. Bardo, Christoph Hiemke, Christoph Hiemke, Lawrence S. Wilkinson, Anthony R. Isles, Celia J. A. Morgan, Valerie H. Curran, Victoria L. Harvey, Anthony H. Dickenson, Mark Slifstein, Jos Prickaerts, David E. Nichols, Lawrence H. Price, Marc N. Branch, Mohammed Shoaib, Jill B. Becker, Marilyn E. Carroll, Peter A. Santi, Marilyn E. Carroll, Peter A. Santi, Juan J. López-Ibor, Maria-Inés López-Ibor, Maria-Inés López-Ibor, Juan J. López-Ibor, Berend Olivier, Naheed (Max) Mirza, Seiya Miyamoto, Mohammed Shoaib, Bernard Le Foll, Cyril Höschl, Sander Nieuwenhuis, Mischa de Rover, Mischa de Rover, Sander Nieuwenhuis, David S. Baldwin, Cyril Höschl, Thomas Steckler, Michel Billiard, Linda Lundström, Will Spooren, Silvia Gatti McArthur, Linda Lundström, Silvia Gatti McArthur, Will Spooren, Darrel J. Pemberton, Kim Wolff, Andrea Bari, Josee E. Leysen, Samuel B. Hutton, Amee B. Patel, Kim Fromme, Kim Fromme, Amee B. Patel, Kim Fromme, Amee B. Patel, Kim Fromme, Amee B. Patel, Suzanne H. Mitchell, Harriet de Wit, Matthew I. Palmatier, Rick A. Bevins, Victoria L. Harvey, Anthony H. Dickenson, David S. Tait, Verity J. Brown, W. Wolfgang Fleischhacker, Samuel B. Hutton +146 moreopenaire +2 more sourcesThe Excitotoxic Concept
1997 This chapter presents an overview of the excitotoxic concept and its putative involvement in hypoxic–ischemic brain damage. Excitotoxicity refers to the central neuronal injury or death induced by glutamate or related excitatory amino acids. Most excitotoxicity is mediated by glutamate receptors, although prolonged exposure to very high concentrations ...openaire +1 more source
