Results 111 to 120 of about 252,625 (305)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Living in Limbo: Existential Concerns Among Greek Young Adults
YouthExistential concerns are particularly salient during emerging adulthood—a period marked by identity exploration, uncertainty, and developmental transitions. This qualitative study explores the existential anxieties of Greek young adults within the unique
Dimitrios Pavlidis +1 more
doaj +1 more source
, 2013 It is claimed hereby that, against a current view of logic as a theory of consequence, opposition is a basic logical concept that can be used to define consequence itself.
Schang, Fabien
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
“I´m the one who has written this”: reciprocity in writing courses for older adults in Norway
International Journal of Qualitative Studies on Health & Well-Being, 2019 Purpose: The aim of this article is to explore, theoretically and empirically, the reciprocity of care afforded by writing courses as community interventions for older adults.
Olga V. Lehmann, Svend Brinkmann
doaj +1 more source
From Yeezus to Pablo: An Existential Theology between God, Blackness, and Being [PDF]
, 2018 Kanye West has transformed and transfigured from a young rapper representing the Southside of Chicago, to an icon, a rap genius, a god. His persona has continually evolved from his arrival on the Hip Hop scene, leading to his emergence as, Yeezus. This
Watts, Shea
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Preaching to Episodic Ears: Practicing a Dramaturgical Homiletic
, 2019 This article is a critical attempt to develop a homiletic methodology for preaching to the episodic self of the 21st century. The British philosopher Galen Strawson contends that postmodern people today do not regard themselves as living out their lives ...
Yang, Sunggu
core
, 1994 In this paper, I will discuss some aspects of a humanistic perspective on love which includes both idealistic as well as realistic elements of love.
Wautischer, Helmut
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source