Results 101 to 110 of about 167,613 (264)

Nonlytic Exocytosis of Cryptococcus neoformans from Macrophages Occurs In Vivo and Is Influenced by Phagosomal pH

open access: yesmBio, 2011
A unique aspect of the interaction of the fungus Cryptococcus neoformans with macrophages is the phenomenon of nonlytic exocytosis, also referred to as “vomocytosis” or phagosome extrusion/expulsion, which involves the escape of fungal cells from the ...
André Moraes Nicola   +4 more
doaj   +1 more source

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

open access: yes, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Ahnert-Hilger, G.   +5 more
core   +1 more source

The beta-neurexin/neuroligin-1 interneuronal intrasynaptic adhesion is essential for quantum brain dynamics [PDF]

open access: yesarXiv, 2002
There are many blank areas in understanding the brain dynamics and especially how it gives rise to consciousness. Quantum mechanics is believed to be capable of explaining the enigma of conscious experience, however till now there is not good enough model considering both the data from clinical neurology and having some explanatory power. In this paper
arxiv  

A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry. [PDF]

open access: yes, 2018
Psychoactive compounds such as chloroquine and amphetamine act by dissipating the pH gradient across intracellular membranes, but the physiological mechanisms that normally regulate organelle pH remain poorly understood.
Bendor, Jacob   +10 more
core   +3 more sources

A Novel Anti-Inflammatory Effect for High Density Lipoprotein.

open access: yesPLoS ONE, 2015
High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL) are attributed to changes in cell adhesion molecules ...
Scott J Cameron   +5 more
doaj   +1 more source

Lysosomal exocytosis and lipid storage disorders

open access: yesJournal of Lipid Research, 2014
Lysosomes are acidic compartments in mammalian cells that are primarily responsible for the breakdown of endocytic and autophagic substrates such as membranes, proteins, and lipids into their basic building blocks. Lysosomal storage diseases (LSDs) are a
M. Samie, Haoxing Xu
semanticscholar   +1 more source

Cyclic AMP signalling in pancreatic islets [PDF]

open access: yes, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian   +2 more
core   +1 more source

Human pancreatic islet miRNA-mRNA networks of altered miRNAs due to glycemic status

open access: yesiScience, 2022
Summary: MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression via mRNA targeting, playing important roles in the pancreatic islets. We aimed to identify molecular pathways and genomic regulatory regions associated with altered miRNA
Alexandros Karagiannopoulos   +5 more
doaj  

Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction [PDF]

open access: yes, 2017
Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells.
Bertone Cueto, Nicolás Iván   +5 more
core   +1 more source

Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]

open access: yesScience's STKE (electronic resource) : signal transduction knowledge environment 327 (21/03/2006) 13, 2007
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv  

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