Results 181 to 190 of about 99,750 (290)

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Stathmin-2 mediates paracrine hormone regulation of glucagon through lysosomal trafficking in αTC1-6 cells. [PDF]

J Physiol
Chang N, Ugulini S, Dhanvantari S.
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Postnatal refinement of Ca_V channel isoform composition, electrical activity, and insulin release in mouse pancreatic β-cells. [PDF]

Channels (Austin)
Theiner T, Jacobo-Piqueras N, Tota D, Tuluc P.   +3 more
europepmc   +1 more source

A Conceptual Framework for Understanding Intelligent Behavior in Fungal Mycelia

Topics in Cognitive Science, EarlyView.
Abstract Fungi exhibit remarkably complex behavior through their mycelial networks, which consist of thread‐like structures known as hyphae. Recent research on saprotrophic fungi has demonstrated that their mycelium behaves in ways that indicate memory, learning, decision‐making, and problem‐solving based on spatial pattern recognition—all of which are
Yu Fukasawa
wiley   +1 more source

TFEB and MCOLN1 are important for <i>Coxiella burnetii</i> egress via lysosomal exocytosis. [PDF]

Front Cell Infect Microbiol
Rinkel S, Schulze-Luehrmann J, Kadavil Baburaj B, Weber F, Liebler-Tenorio EM, Lührmann A.   +5 more
europepmc   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

SARS-CoV-2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release. [PDF]

mLife
Qin F, Yan C, Liu Z, Wang D, Zhong H, Ding Q, Chen M, Zhang XE.   +7 more
europepmc   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source