Results 171 to 180 of about 99,750 (290)

The Psoriasis–Eczema Interface: Clinical Classification and Therapeutic Implications From a Bicentric Experience

open access: yesInternational Journal of Dermatology, EarlyView.
The psoriasis–atopic dermatitis interface: four clinical phenotypes (coexisting, overlapping, biologic‐induced eczema, dupilumab‐induced psoriasis) across 105 patients from two Italian tertiary centers. JAK inhibitors achieved the highest response rates across all phenotypes, reflecting their mechanistic rationale targeting shared JAK‐STAT downstream ...
Michela D'Agostino   +8 more
wiley   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó   +4 more
wiley   +1 more source

ExoFILT: transfer learning for robust and accelerated analysis of exocytosis single-particle tracking data. [PDF]

open access: yesBioinformatics
Kramer E   +6 more
europepmc   +1 more source

The homologous GRAS transcription factors RAM1 and RAD1 coordinate shared and separate gene networks to regulate arbuscular mycorrhiza symbiosis

open access: yesNew Phytologist, EarlyView.
Mutations in RAM1 and RAD1 have different effects on arbuscule development in Lotus japonicus. Summary Arbuscular mycorrhiza (AM), a symbiosis between plants and Glomeromycotan fungi is based on the exchange of nutrients, which majorly occurs between fungal tree‐shaped arbuscules and root cortex cells.
Tian Zeng   +6 more
wiley   +1 more source

Pediatric Langerhans Cell Histiocytosis Presenting With Bilateral Parotid Gland Swelling and Cystic Lung Disease: A Case Report and Literature Review

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Langerhans cell histiocytosis (LCH) is a neoplastic process originating from immature myeloid precursor cells. In this report, we describe a case of a 17‐month‐old with scaling of the scalp and swelling of the bilateral parotid glands who developed acute respiratory distress.
Aretha On   +4 more
wiley   +1 more source

A Germline Missense Variant in the NSDHL Gene Underlies Inflammatory Linear Verrucous Epidermal Nevus

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disorder characterized by pruritic, erythematous, and scaly plaques following Blaschko's lines. Known genetic causes include somatic variants in CARD14 and GJA1. In addition, a similar phenotype of congenital hemidysplasia with ichthyosiform nevus and limb defects (CHILD ...
Janan Mohamad   +10 more
wiley   +1 more source

Development of a Photostable pH Biosensor Based on mStayGold. [PDF]

open access: yesChembiochem
Chang M   +7 more
europepmc   +1 more source

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