Results 111 to 120 of about 265,040 (167)

Applications and challenges of dsRNA-mediated RNAi in aquaculture

Water Biology and Security
Aquaculture plays a vital role in the global food supply but continues to face considerable challenges, including frequent disease outbreaks, low production efficiency, and environmental pollution.
Lihui Meng, Xintong Zhang, Min Zhou, Yi Wu, Jinyong Zhang   +4 more
doaj   +1 more source

Tumour‐Derived Extracellular Vesicles Containing dsRNA Induce Degradation of Ribosomal Protein mRNA in Platelets

Journal of Extracellular Vesicles
Extracellular vesicles (EVs) mediate intercellular communication within the tumour microenvironment by carrying cargoes from paracrine parent cells. EVs have attracted great research interest for their ability to carry nucleic acids into recipient cells ...
Gaoge Sun, Yuhuan Tao, Zihan Liu, Kaixiang Zhang, Shuai Zuo, Shanwen Chen, Shufang Ning, Tianyi Zhang, Pengyuan Wang, Ying Zhang, Zhi John Lu, Hang Hubert Yin   +11 more
doaj   +1 more source

Evolutionary History and Population Dynamics of the M2 Double-stranded RNA of Rhizoctonia solani

, 2008
M2 is a 3.57 kb double-stranded RNA (dsRNA) mycovirus first identified and sequenced from the soil fungus Rhizoctonia solani anastomosis group 3 (AG-3).
Charlton, Nikki De-Roi
core  

Exogenous Application of IR-Specific dsRNA Inhibits Infection of Cucumber Green Mottle Mosaic Virus in Watermelon

Cucumber green mottle mosaic virus (CGMMV) represents a serious threat in the production of watermelon. Small RNAs facilitate a mechanism known as RNA interference (RNAi), which regulates gene expression.
Baoshan Kang, Qinsheng Gu, Chaoxi Luo, Yanhui Wang, Yongqiang Fan, Yanli Han, Liming Liu, Zhiling Liang, Yanfei Geng, Fengnan Liu   +9 more
core   +1 more source

Delivery of dsRNA for RNAi in insects: An overview and future directions

, 2013
RNA interference (RNAi) refers to the process of exogenous double-stranded RNA (dsRNA) silencing the complementary endogenous messenger RNA. RNAi has been widely used in entomological research for functional genomics in a variety of insects and its ...
J. Niu, H. Huvenne, CACCIA, SILVIA, J. Liu, Yu, Na, Niu, Jinzhi, Huvenne, Hanneke, G. Smagghe, Smagghe, Guy, Cappelle, Kaat, N. Yu, S. Caccia, Liu, Jisheng, Christiaens, Olivier, O. Christiaens, K. Cappelle   +15 more
core   +1 more source

Cellular uptake of extracellular dsRNA is tissue-dependent in insects

BMC Biology
Background RNA interference (RNAi), a naturally occurring gene silencing mechanism found in almost all eukaryotic organisms, has proven to be an adaptable and powerful tool in therapeutics, bioengineering, and agriculture. Differential responses to RNAi,
Xuekai Shi, Yaoming Liu, Xiaojian Liu, Mureed Abbas, Austin Merchant, Hans Merzendorfer, Zhangwu Zhao, Xuguo Zhou, Kun Yan Zhu, Jianzhen Zhang   +9 more
doaj   +1 more source

Feeding exogenous dsRNA interferes with endogenous sRNA accumulation in Paramecium. [PDF]

DNA Res, 2020
Karunanithi S, Oruganti V, de Wijn R, Drews F, Cheaib M, Nordström K, Simon M, Schulz MH.   +7 more
europepmc   +1 more source

Cellular dsRNA interactome reveals the regulatory map of exogenous RNA sensing

RNA-binding proteins (RBPs) provide a critical post-transcriptional regulatory layer in determining RNA fate. Currently, UV crosslinking followed by oligo-dT pull-down is the gold standard in identifying the RBP repertoire, but such method is ineffective
Ju, Seonmin, Kim, Sujin, LEE, NAMSEOK, Bae, Sangsu, Kim, Yoosik, LEE, YONG KI, Kim, Jisoo, Lim, JinA, Ku, Jayoung, Lee, Seok-Hoon, Mun, Subin, Kim, Jong-Seo   +11 more
core  

RNA interference protocols for gene silencing in the spittlebug Philaenus spumarius, vector of Xylella fastidiosa

Scientific Reports
RNA interference (RNAi) is double stranded RNA (dsRNA)-based gene silencing mechanism. Exogenous dsRNAs application to crops has raised as a powerful tool to control agricultural pests.
Cecilia Parise, Luciana Galetto, Simona Abbà, Nicola Bodino, Cristina Marzachì, Domenico Bosco   +5 more
doaj   +1 more source

Identification and application of exogenous dsRNA confers plant protection against Sclerotinia sclerotiorum and Botrytis cinerea. [PDF]

Sci Rep, 2018
McLoughlin AG, Wytinck N, Walker PL, Girard IJ, Rashid KY, de Kievit T, Fernando WGD, Whyard S, Belmonte MF.   +8 more
europepmc   +1 more source