Results 91 to 100 of about 265,040 (167)

Induction of viral resistance in plants by dsRNA interference

, 2005
Double-stranded RNA (dsRNA) has been shown to promote interference of gene expression of endogenous genes that contain homologous sequences. This interference is referred to as post-transcriptional gene silencing or PTGS.
DeLany, Thomas
core   +3 more sources

Identification of pathogenicity determinants in ToLCNDV and their RNAi-based knockdown for disease management in Nicotiana benthamiana and tomato plants

Frontiers in Microbiology
Begomovirus solanumdelhiense (tomato leaf curl New Delhi virus, ToLCNDV), is member of the genus Begomovirus, family Geminiviridae, is a prolific bipartite whitefly transmitted begomovirus in the Indian sub-continent has a wide host range, including ...
Mehulee Sarkar, Dipinte Gupta, Oinam Washington Singh, Samrat Paul, Ravinder Kumar, Bikash Mandal, Anirban Roy   +6 more
doaj   +1 more source

How Epitranscriptomic Machinery Senses Environmental Cues

Advanced Biology, Volume 10, Issue 9, September 2026.
Exogenous exposures, microenvironmental signals, and intracellular metabolic or redox states can alter RNA‐modification machinery through catalytic chemistry, signaling‐dependent PTMs, compartmental redistribution, or changes in abundance and composition.
Shayan Jalali, Ehsan Pashay Ahi
wiley   +1 more source

Exogenous dsRNA-Induced Silencing of the Phytophthora infestans Elicitin Genes inf1 and inf4 Suppresses Its Pathogenicity on Potato Plants. [PDF]

J Fungi (Basel), 2023
Ivanov AA, Golubeva TS.
europepmc   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

mRNA Therapeutics Beyond Infectious Diseases: Expanding Therapeutic Applications and Future Perspectives

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
Messenger RNA therapeutics are rapidly expanding beyond infectious diseases into oncology, autoimmune disorders, protein replacement therapy, cardiovascular and neurological diseases, and regenerative medicine. Advances in RNA engineering and targeted delivery are driving the development of safe, programmable, and precision therapeutics for diverse ...
Gedion Mengistu Dejen
wiley   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Targeted silencing of multiple Fusarium graminearum genes via graphene quantum dots enhances RNAi-based control of Fusarium head blight in wheat

Plant Nano Biology
Fusarium head blight (FHB), caused by the fungus Fusarium graminearum, is a devastating disease of wheat resulting in substantial yield loss and grain contamination with mycotoxins. While chemical fungicides are currently the primary control method, they
Binod Gyawali, Yanhong Dong, Rahim Rahimi, Matthew Helm, Mohsen Mohammadi   +4 more
doaj   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila

International audienceThe small interfering RNA pathway is the primary antiviral defense mechanism in invertebrates and plants. This systemic mechanism relies on the recognition, transport, and internalization of double-stranded RNA (dsRNA).
Vinh, Joelle, Mukherjee, Shaeri, Fletcher, Sabrina, Blanc, Hervé, Verdier, Yann, Saleh, Maria-Carla, P, Bardossy, Eugenia, Moss, Thomas, Tomé-Poderti, Lorena, Frangeul, Lionel, Mongelli, Vanesa   +10 more
core   +1 more source