Results 81 to 90 of about 265,040 (167)

Efficiency of RNAi‐based gene silencing in fungi: a meta‐analysis

New Phytologist, EarlyView.
Mechanistic interpretation of RNAi efficiency across fungal lifestyles and delivery strategies based on the present meta‐analysis. Summary RNA interference (RNAi) shows great potential to protect crops against fungal diseases, yet reported protection efficiencies vary greatly, and our understanding of the factors responsible for this variance remains ...
Patrick Barth, Jakob Drumm, Alexandra Erika Schmidt, Florian Hartig, Aline Koch   +4 more
wiley   +1 more source

Study on a novel dsRNA virus isolated from the white root rot fungus, Rosellinia necatrix Prillieux, W89

, 2010
由白紋羽病菌 (Rosellinia necatrix Prillieux) 所引起之白紋羽病，為常見之植物根腐病害。此病原菌 (無性世代為Dematophora necatrix Prilleux）在分類上屬子囊菌炭角菌科，Rosellinia屬。其寄主範圍廣泛，台灣地區之發病記錄有七種，包括枇杷、梨樹、桃樹、蘋果、櫻花、葡萄、茶樹等。病株受感染後由根部開始枯死進而全株凋萎，以往使用土壤灌注方法施予藥劑雖可達到一定的防治效果，但長期使用化學藥劑除成本高昂外，更對環境造成沉重負擔 ...
Lin, Yu-Hsin, 林諭昕
core  

Exogenous dsRNA-Mediated Control of Rice Blast Fungus Involves Sequence-Specific RNAi and Sequence-Unspecific Fungal Stress Responses

Ladera-Carmona M, Zheng Y, Moorlach BW, et al. Exogenous dsRNA-Mediated Control of Rice Blast Fungus Involves Sequence-Specific RNAi and Sequence-Unspecific Fungal Stress Responses.
Heinlein, Manfred, Kogel, Karl-Heinz, Jakobs-Schönwandt, Désirée, Poranen, Minna, Pastacaldi, Chiara, Sede, Ana, Ladera-Carmona, Maria, Jacob, Stefan, Zheng, Ying, Patel, Anant ; https://orcid.org/, Moorlach, Benjamin Willem ; https://orcid.org/   +10 more
core   +1 more source

RNA interference targets arbovirus replication in Culicoides cells [PDF]

, 2013
Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks and midges. These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organisms.
Varela, Mariana, Esther Schnettler, Ratinier, Maxime, Shaw, Andrew, Palmarini, Massimo, Kohl, Alain, Mariana Varela, Mick Watson, Elliott, Richard M., Alain Kohl, Maxime Ratinier, McFarlane, Melanie, Shaw, Andrew E., Elliott, Richard, Richard M, Massimo Palmarini, Schnettler, Esther, E. Shaw, Watson, Mick, A Alain Kohla, Melanie Mcfarlane   +20 more
core   +1 more source

A New Model of Gastric Pre-neoplasia Induced by Aberrant ADAR1-mediated Double-stranded RNA SignalingSummaryWhat You Need to Know

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Recent evidence suggests that endogenously derived double-stranded RNA (dsRNA) impacts multiple cellular processes, although its role in epithelial injury remains understudied.
Angela M. Halstead, Chinye Nwokolo, Stella Hoft, Jinsheng Yu, Lifei Zhu, Brendan Tuley, Nancy Vargas, RuiRui Liu, Francisco Ramirez Victorino, Simrin Phatak, Wandy Beatty, Chun-Kan Chen, Richard DiPaolo, Paul Cliften, Tarin M. Bigley, José B. Sáenz   +15 more
doaj   +1 more source

Design of Lipopeptides and dsRNA‐Lipopeptide Complexes for Sprayable RNAi‐Based Plant Protection

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Lipopeptide surfactants self‐assemble into nanostructure carriers that complex, protect, and deliver dsRNA, establishing structure–function relationships for next‐generation RNAi‐based insect control. ABSTRACT Broad‐spectrum insecticides persist in the environment, affecting non‐target organisms and selecting for resistant pest populations. In contrast,
Pascal Geisler, Frank Steiniger, Andreas Vilcinskas, Christoph Hellmann   +3 more
wiley   +1 more source

Targeting the DNA Damage Response in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Targeting the DNA damage response (DDR) reshapes both tumor vulnerability and antitumor immunity. DNA lesions and DDR inhibitors can promote cytosolic nucleic‐acid sensing, antigen presentation, and immune activation, but can also induce adaptive immune escape.
Yihuan Qiao, Boyu Kang, Jian Zhang, Rui Zhang, Jipeng Li   +4 more
wiley   +1 more source

Double-strand RNA (dsRNA) delivery methods in Insects: Diaphorina citri

, 2022
RNAi is a gene-silencing mechanism conserved in the vast majority of eukaryotes. It is widely used to study gene function in animals due to the ease of eliciting gene knockdown.
Flynt, Alex, Santos-Ortega, Yulica
core   +1 more source

Identification of broadly expressed nervous system‐related genes as effective RNAi targets in the brown marmorated stink bug, Halyomorpha halys

Pest Management Science, Volume 82, Issue 10, Page 9870-9878, October 2026.
Broadly expressed genes outperformed brain‐enriched neural targets as RNAi candidates in Halyomorpha halys. Microinjection of dsRNA targeting alpha‐soluble NSF attachment protein (Asnap) or Ras opposite protein (Rop) caused strong feeding suppression and near‐complete mortality, identifying them as promising targets for future oral or spray‐based RNAi ...
Nirakar Panda, Aline Koch, Venkata Partha Sarathi Amineni   +2 more
wiley   +1 more source

Exogenous Application of dsRNA—Inducing Silencing of the Fusarium oxysporum Tup1 Gene and Reducing Its Virulence

Fusarium oxysporum is a widespread soil-borne fungal pathogen that can infect various plants, causing wilt and root rot diseases. The root rot disease of Atractylodes macrocephala caused by F.
Yunjia Tang, Sen Fan, Yujin Zhao, Shijie Dai, Na Zhu, Yanguang Zhou, Jingyan Xu, Xiaofeng Yuan, Qingling Meng   +8 more
core   +1 more source