Results 71 to 80 of about 265,040 (167)

Effects of Double-Stranded RNA Degrading Nucleases on RNAi Efficiency in Beet Moth Spodoptera exigua (Lepidoptera: Noctuidae)

Insects
The insect order Lepidoptera contains many species that are considered to be agricultural pests. Specific double-stranded RNA-degrading enzymes in some moth species decrease the efficiency of RNA interference (RNAi).
Guandi Wang, Qian Wang, Wenrui Liu, Jingxin Wen, Yubo Yang, Zhilong Niu, Wei Guo, Dan Zhao   +7 more
doaj   +1 more source

A horizontally transferred bacterial gene for pantothenic acid biosynthesis regulates diapause and reproduction in the spider mite Amphitetranychus viennensis

Insect Science, EarlyView.
A bacterial‐derived AvPBL gene encoding a pantothenate‐β‐alanine ligase was identified in Amphitetranychus viennensis. RNAi silencing of AvPBL reduced pantothenic acid production, impairing reproduction and diapause induction, while pantothenic acid supplementation rescued these phenotypes.
Meibin Liu, Yifei Wang, Yikang Ren, Fan Yang, Meifeng Ren, Qin Yu, Xuguo Zhou, Zezhong Yang, Jing Yang   +8 more
wiley   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA. [PDF]

, 2013
The DExD/H box RNA helicases retinoic acid-inducible gene-I (RIG-I) and melanoma differentiation associated gene-5 (mda-5) sense viral RNA in the cytoplasm of infected cells and activate signal transduction pathways that trigger the production of type I ...
Kay S Childs, Richard E. Randall (190211), Randall, RE, Stephen Goodbourn (411674), Goodbourn, Stephen, Kay S. Childs (411673), Richard E. R, Goodbourn, S, Childs, Kay S., Childs Kay S., Richard E Randall, Randall Richard E., Randall, Richard E., Kay S. Childs, Stephen Goodbourn, Childs, KS, Goodbourn Stephen   +16 more
core   +2 more sources

SID-1 is a dsRNA-Selective dsRNA-gated Channel [PDF]

, 2011
Systemic RNAi in Caenorhabditis elegans requires the widely conserved transmembrane protein SID-1 to transport RNAi silencing signals between cells. When expressed in Drosophila S2 cells, C.
Joseph D. Shih, Craig P. Hunter, Hunter, Craig, Shih, Joseph D.   +3 more
core   +2 more sources

RNA activation in insects: From emerging evidence to molecular applications

Insect Molecular Biology, EarlyView.
Canonical RNA activation involves small RNAs interacting with promoter sequences, but there is also evidence of non‐canonical RNAa in eukaryotes. Emerging evidence suggests the presence of RNAa in insects. RNAa can be utilised as a tool for functional genomic studies in insects.
Sassan Asgari
wiley   +1 more source

Engineered Yarrowia lipolytica inducing gene silencing confers control ability against gray mold in plants

Journal of Integrative Plant Biology, EarlyView.
Engineered the plant‐colonizing yeast Yarrowia lipolytica to produce and deliver double‐stranded RNAs targeting key genes of the gray mold fungus Botrytis cinerea produced a ‘living factory’ that continuously synthesizes and releases gene‐silencing molecules on plant surfaces, effectively suppressing the pathogen.
Mengjie Liu, Heng Shen, Jie Li, Mei Hao, Yelei Sun, Wenxing Liang   +5 more
wiley   +1 more source

Exogenous Application of dsRNA for Protection against Tomato Leaf Curl New Delhi Virus

, 2023
Tomato leaf curl New Delhi virus (ToLCNDV) is an emerging plant pathogen, fast spreading in several Asian and Mediterranean regions, considered the most harmful geminivirus infecting cucurbits in the Mediterranean.
Anna Maria Vaira, Fulco Frascati, Daniele Marian, Gian Paolo Accotto, Emanuela Noris, Laura Miozzi   +5 more
core  

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Comparative Analysis of In Vitro vs. In Vivo dsRNA Production for CHS Silencing and Downstream Flavonoid Pathway Suppression in Arabidopsis thaliana

International Journal of Plant Biology
Exogenously induced RNA interference (exoRNAi) is a powerful biotechnology tool for precise gene regulation. The plant chalcone synthase (CHS) gene serves as a valuable model for molecular biology due to its central role in flavonoid biosynthesis ...
Andrey R. Suprun, Stanislava A. Vinogradova, Konstantin V. Kiselev, Nikolay N. Nityagovsky, Alexandra S. Dubrovina   +4 more
doaj   +1 more source