Results 51 to 60 of about 265,040 (167)

Exogenous RNAi to control rust fungi

open access: yes, 2022
Exogenous RNA interference (RNAi) is an effective non-genetically modified (GM) control strategy for plant viruses, insect pests, fungal and oomycete pathogens.
Degnan, Rebecca M.   +4 more
core   +2 more sources

Strigolactone signaling: Licensing antiviral RNA interference in rice

open access: yesNew Plant Protection, EarlyView.
Rice grassy stunt virus (RGSV) suppresses strigolactone‐mediated antiviral RNAi through P3‐D14 interaction. Structure‐guided D14D102N editing disrupts P3 binding while maintaining SL signaling, sustaining antiviral defense and providing strong resistance without compromising plant growth or yield.
Kaibo Gu, Yanjun Li
wiley   +1 more source

Transcriptomic resources and functional validation of RNAi in the cabbage seedpod weevil, Ceutorhynchus obstrictus

open access: yesPest Management Science, EarlyView.
Transcriptome sequencing of Ceutorhynchus obstrictus revealed RNA interference (RNAi) targets; double‐stranded RNA microinjection reduced transcript levels and increased mortality, with αCOP and Rop showing strongest lethal effects, indicating promising RNAi‐based pest control candidates.
Apurva Vikas Sabnis   +8 more
wiley   +1 more source

The in vivo dsRNA Cleavage Has Sequence Preference in Insects

open access: yesFrontiers in Physiology, 2018
Exogenous dsRNA enters the insect body and can induce the RNAi effect only when it is cleaved into siRNA. However, what kinds of base composition are easier to cut and what kinds of siRNA will be produced in vivo is largely unknown.
Ruobing Guan   +6 more
doaj   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

open access: yesPest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti   +3 more
wiley   +1 more source

The first RNAi‐based biopesticide approved in the United States: regulatory implications for the European Union – the case of Ledprona (Calantha™)

open access: yesPest Management Science, EarlyView.
The approval of the RNA interference‐based biopesticide Ledprona (Calantha™) in the USA marks a milestone for RNA‐based crop protection. We discuss the regulatory implications for the European Union, highlighting opportunities, challenges, and the need for adapted risk assessment frameworks for RNA‐based plant protection products.
Aline Koch, Gabi Krczal
wiley   +1 more source

Analysis of small RNA populationsgenerated in peanut leaves after exogenous application of dsRNA and dsDNA targeting aflatoxin synthesis genes [PDF]

open access: yes, 2020
Previously, we have shown that RNA interference (RNAi) can prevent aflatoxin accumulation in transformed peanuts. To explore aflatoxin control by exogenous delivery of double-strand RNA (dsRNA) it is necessary to understand the generation of small RNA ...
Orner, Valerie A.   +7 more
core  

Production of functional double‐stranded RNA using a prokaryotic expression system in Escherichia coli

open access: yesMicrobiologyOpen, 2019
RNA interference (RNAi) is a nucleic acid metabolism system utilized for the post‐translational regulation of endogenous genes or for defense against exogenous RNA or transposable elements.
Zhengjun Chen   +4 more
doaj   +1 more source

MicroRNA-directed siRNA biogenesis in Caenorhabditis elegans. [PDF]

open access: yesPLoS Genetics, 2010
RNA interference (RNAi) is a post-transcriptional silencing process, triggered by double-stranded RNA (dsRNA), leading to the destabilization of homologous mRNAs. A distinction has been made between endogenous RNAi-related pathways and the exogenous RNAi
Régis L Corrêa   +3 more
doaj   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

open access: yesVIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore   +5 more
wiley   +1 more source

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