Results 51 to 60 of about 22,111 (197)

In vivo dsRNA production system for silencing the phytoene desaturase gene of potato Solanum tuberosum [PDF]

E3S Web of Conferences
In this work, for the first time, an in vivo system was developed for the production of exogenous double-stranded RNA (dsRNA), complementary to the potato phytoene desaturase (pds) gene.
Ivanov Artemii, Golubeva Tatiana
doaj   +1 more source

Optimizing Efficient RNAi-Mediated Control of Hemipteran Pests (Psyllids, Leafhoppers, Whitefly): Modified Pyrimidines in dsRNA Triggers

Plants, 2021
The advantages from exogenously applied RNAi biopesticides have yet to be realized in through commercialization due to inconsistent activity of the dsRNA trigger, and the activity level of RNAi suppression.
Wayne Brian Hunter, William M. Wintermantel   +1 more
doaj   +1 more source

New insights into control of arbovirus replication and spread by insect RNA interference pathways [PDF]

, 2012
Arthropod-borne (arbo) viruses are transmitted by vectors, such as mosquitoes, to susceptible vertebrates. Recent research has shown that arbovirus replication and spread in mosquitoes is not passively tolerated but induces host responses to control ...
Andersson, Angelini, Angelini, Arensburger, Arensburger, Attarzadeh-Yazdi, Berry, Blevins, Brackney, Chung, Cirimotich, Cohen, Czech, Ding, Dubrulle, Fagegaltier, Flynt, Franz, Ghildiyal, Henke, Holt, Hussain, Hussain, Iwasaki, Kaminker, Kawamura, Keene, Kwon, Lagos-Quintana, Li, Lim, Lucchetta, Mendes, Morazzani, Mueller, Myles, Nene, Qi, Rezza, Ruby, Saleh, Sanchez-Vargas, Schwarz, Selbach, Sijen, Siu, Skalsky, Tam, Thibault, Vodovar, Watanabe, Waterhouse, Wu, Yan, Zeiner, Zeng   +55 more
core   +3 more sources

CAPA neuropeptides and their receptor form an anti-diuretic hormone signalling system in the human disease vector, Aedes aegypti [PDF]

, 2020
Insect CAPA neuropeptides are homologs of mammalian neuromedin U and are known to influence ion and water balance by regulating the activity of the Malpighian ‘renal’ tubules (MTs).
Ber, Lindsay Taylor, Lajevardi, Aryan, Matei, Andreea, Paluzzi, Jean-Paul, Paputsis, Christine, Sajadi, Farwa, Uyuklu, Ali, Wahedi, Azizia   +7 more
core   +1 more source

Exogenous and endogenous dsRNAs perceived by plant Dicer-like 4 protein in the RNAi-depleted cellular context

Cellular & Molecular Biology Letters, 2023
Abstract Background In plants, RNase III Dicer-like proteins (DCLs) act as sensors of dsRNAs and process them into short 21- to 24-nucleotide (nt) (s)RNAs. Plant DCL4 is involved in the biogenesis of either functional endogenous or exogenous (i.e. viral) short interfering (si)RNAs, thus playing crucial antiviral roles.
Leonetti P, Consiglio A, Arendt D, Golbik RP, Rubino L, Gursinsky T, Behrens SE, Pantaleo V   +7 more
openaire   +5 more sources

Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L [PDF]

, 2017
Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans.
Chen, Annie I, Elliott, Ruth, Goldstein, Stephen A, Jha, Babal K, Li, Yize, Quiroz-Figueroa, Katherine, Silverman, Robert H, Thornbrough, Joshua M, Weiss, Susan R, Zhang, Rong   +9 more
core   +2 more sources

The possible impact of persistent virus infection on the function of the RNAi machinery in insects: a hypothesis

Frontiers in Physiology, 2013
RNAi experiments in insects are characterized by great variability in efficiency; for instance beetles and locusts are very amenable to dsRNA-mediated gene silencing, while other insect groups, most notably lepidopterans, are more refractory to RNAi ...
Luc eSwevers, Jozef eVanden Broeck, Guy eSmagghe   +2 more
doaj   +1 more source

Cigarette Smoke Suppresses Type I Interferon-Mediated Antiviral Immunity in Lung Fibroblast and Epithelial Cells [PDF]

, 2008
The objective of this study was to investigate the impact of cigarette smoke on innate antiviral defense mechanisms; specifically, we examined the effects of cigarette smoke on the induction of type I interferon (IFN).
Bauer, Carla M.T., DeWitte-Orr, Stephanie J., Hornby, Kyle R., Lichty, Brian D., Mossman, Karen L., Stämpfli, Martin R., Zavitz, Caleb C.J.   +6 more
core   +2 more sources

Exogenous dsRNA made accessible to Dicer by two eukaryotic RNA-dependent RNA polymerases in Paramecium tetraurelia

Communications Biology
Discrimination of self from non-self RNA is a critical requirement for any cell to respond to infections and to maintain cellular integrity. We report novel functions for two RNA-dependent RNA polymerases (RDRs) in Paramecium.
Marcello Pirritano, Johannes Buescher, Pauline Staubach, Thorsten Tacken, Yulia Yakovleva, Mark Sabura, Kristela Shehu, Sören Franzenburg, Marc Schneider, Martin Simon   +9 more
doaj   +1 more source

RNA interference targets arbovirus replication in Culicoides cells [PDF]

, 2013
This work was supported by United Kingdom Medical Research Council and Wellcome Trust.Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks, and midges.
Elliott, Richard M., Kohl, Alain, McFarlane, Melanie, Palmarini, Massimo, Ratinier, Maxime, Schnettler, Esther, Shaw, Andrew E., Varela, Mariana, Watson, Mick   +8 more
core   +3 more sources