Results 41 to 50 of about 22,111 (197)

The South American fruit fly : an important pest insect with RNAi-sensitive larval stages [PDF]

open access: yes, 2019
RNA interference (RNAi) technology has been used in the development of approaches for pest control. The presence of some essential genes, the so-called "core genes," in the RNAi machinery is crucial for its efficiency and robust response in gene ...
Cagliari, Deise   +6 more
core   +1 more source

First Evidence of Bud Feeding-Induced RNAi in a Crop Pest via Exogenous Application of dsRNA [PDF]

open access: yesInsects, 2020
Spray-induced gene silencing (SIGS) is a potential strategy for agricultural pest management, whereby nucleotide sequence-specific double-stranded RNA (dsRNA) can be sprayed onto a crop; the desired effect being a consumption of dsRNA by the target pest, and subsequent gene silencing-induced mortality.
Jonathan Willow   +8 more
openaire   +5 more sources

Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]

open access: yes, 2013
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L.   +8 more
core   +3 more sources

A novel sustainable platform for scaled manufacturing of double-stranded RNA biopesticides

open access: yesBioresources and Bioprocessing, 2022
RNA interference (RNAi) represents one of the most conserved pathways evolved by eukaryotic cells for regulating gene expression. RNAi utilises non-translatable double-stranded RNA (dsRNA) molecules to sequester or degrade mRNA molecules gene.
Alison Obinna Nwokeoji   +3 more
doaj   +1 more source

Reduction in Musca domestica fecundity by dsRNA-mediated gene knockdown. [PDF]

open access: yesPLoS ONE, 2018
House flies (Musca domestica) are worldwide agricultural pests with estimated control costs at $375 million annually in the U.S. Non-target effects and widespread resistance challenge the efficacy of traditional chemical control.
Neil D Sanscrainte   +7 more
doaj   +1 more source

Viral RNA at two stages of reovirus infection is required for the induction of necroptosis [PDF]

open access: yes, 2017
Necroptosis, a regulated form of necrotic cell death, requires the activation of the RIP3 kinase. Here, we identify that infection of host cells with reovirus can result in necroptosis.
Berger, Angela K   +6 more
core   +2 more sources

Clathrin mediated endocytosis is involved in the uptake of exogenous double-stranded RNA in the white mold phytopathogen Sclerotinia sclerotiorum

open access: yesScientific Reports, 2020
RNA interference (RNAi) technologies have recently been developed to control a growing number of agronomically significant fungal phytopathogens, including the white mold pathogen, Sclerotinia sclerotiorum.
Nick Wytinck   +6 more
doaj   +1 more source

Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]

open access: yes, 2013
Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl   +17 more
core   +3 more sources

The antiviral RNAi response in vector and non-vector cells against orthobunya viruses [PDF]

open access: yes, 2017
Background: Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and
Bausch, DG   +9 more
core   +5 more sources

Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans. [PDF]

open access: yes, 2015
UNLABELLED: Antiviral RNA-mediated silencing (RNA interference [RNAi]) acts as a powerful innate immunity defense in plants, invertebrates, and mammals. In Caenorhabditis elegans, RNAi is systemic; i.e., RNAi silencing signals can move between cells and ...
Ashe, Alyson   +4 more
core   +5 more sources

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