Results 211 to 220 of about 419,485 (330)

A 5.3-kb deletion including exon XIII of the protein S alpha gene occurs in two protein S-deficient families [see comments] [PDF]

, 1991
DK Schmidel, R G Nelson, EH Jr Broxson, PC Comp, RA Marlar, GL Long   +5 more
openalex   +1 more source

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

Advanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren, Junjun Qiu, Fanghua Chen, Qian Jiang, Qinqin Liu, Tong Wu, Hua Jiang, Keqin Hua   +7 more
wiley   +1 more source

Genetic Correlates of Presenile Dementia and Cognitive Decline in the Armenian Population Following COVID-19: A Case-Control Study. [PDF]

Int J Mol Sci
Hovhannisyan Y, Yeritsyan H, Hakobjanyan G, Petrosyan G, Harutyunyan H, Muradyan A, Azizian A, Yenkoyan K.   +7 more
europepmc   +1 more source

Individual exons encode the integral membrane domains of human myelin proteolipid protein.

, 1986
H J Diehl, Markus Schaich, Ralph-Michael BUDZINSKI, W. Stoffel   +3 more
openalex   +1 more source

Base pairing between the 3' exon and an internal guide sequence increases 3' splice site specificity in the Tetrahymena self-splicing rRNA intron. [PDF]

, 1990
E R Suh, Richard B. Waring
openalex   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Compensatory Evolution Following Deleterious Episodes of GC-biased Gene Conversion in Rodents. [PDF]

Mol Biol Evol
Riffis M, Saclier N, Galtier N.
europepmc   +1 more source

Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

Advanced Science, EarlyView.
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng, Jiayao Li, Wuke Wang, Dong Liang, Zhanwei Li, Cong Mao, Qingyang Li, Yu Zhang, Hao Chen, Jin Tang, Ping Hu, Qi Niu, Xingxu Huang, Bin Shen, Jun Zhang   +14 more
wiley   +1 more source

Molecular basis of backsplicing regulation and its application to manipulate circRNA levels. [PDF]

RNA Biol
Wang Y, Dzakah EE, Wang X.
europepmc   +1 more source

Sequence homology between bacteriorhodopsin and G‐protein coupled receptors: exon shuffling or evolution by duplication? [PDF]

, 1993
Ethan Will Taylor, Atul Agarwal
openalex   +1 more source