Results 51 to 60 of about 18,176 (172)
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu +7 more
wiley +1 more source
Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs
Subgenomic flavivirus RNAs are generated by a host exoribonuclease and play an important role in virus replication and pathogenesis. Here, the authors show the mechanism by which subgenomic flavivirus RNAs are generated and identify two structurally ...
Andrea MacFadden +8 more
doaj +1 more source
Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt +37 more
core +2 more sources
ZSWIM8, an E3 ubiquitin ligase that broadly targets IDR‐rich proteins, drives MiR‐7‐dependent AGO2 degradation and the turnover of many RBPs. Loss of ZSWIM8 leads to MiR‐7 accumulation in oligodendrocyte progenitor cells and myelination defects in the developing brain. ABSTRACT Proteostasis of proteins with intrinsically disordered regions (IDRs) is of
Jing Lei +13 more
wiley +1 more source
The mitochondrial RNA degradosome (mtEXO) plays an essential role in the regulation of mitochondrial gene expression and is composed of the 3′-to-5′ exoribonuclease Dss1 and the helicase Suv3.
Michal Razew +12 more
doaj +1 more source
Uridylation and adenylation of RNAs. [PDF]
The posttranscriptional addition of nontemplated nucleotides to the 3' ends of RNA molecules can have a significant impact on their stability and biological function.
Chen, XueMei +3 more
core +2 more sources
Novel roles of sulfur metabolism in stress‐controlled stomata aperture regulation
Summary Stomatal closure allows plants to conserve water by reducing transpiration during drought. Surprisingly, the assimilation of the macronutrient sulfur is intimately connected to the drought stress response. This Tansley insight will only briefly touch on the general impact of sulfate assimilation on the production of drought‐response metabolites.
Sheng‐Kai Sun +2 more
wiley +1 more source
Inflorescence stem grafting made easy in Arabidopsis [PDF]
UNLABELLED BACKGROUND Plant grafting techniques have deepened our understanding of the signals facilitating communication between the root and shoot, as well as between shoot and reproductive organs.
Cazzonelli, Christopher I +3 more
core +1 more source
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang +10 more
wiley +1 more source
Promotion of Bamboo mosaic virus accumulation in Nicotiana benthamiana by 5’→3’ exonuclease NbXRN4
Bamboo mosaic virus (BaMV) has a 6.4-kb (+) sense RNA genome with a 5’ cap and a 3’ poly(A) tail. ORF1 of this potexvirus encodes a 155-kDa replication protein responsible for the viral RNA replication/transcription and 5’ cap formation.
Cheng-Cheng eLee +6 more
doaj +1 more source

