Results 41 to 50 of about 3,495 (190)
Biochemical Characterization of Exoribonuclease Encoded by SARS Coronavirus [PDF]
BMB Reports, 2007 The nsp14 protein is an exoribonuclease that is encoded by severe acute respiratory syndrome coronavirus (SARS-CoV). We have cloned and expressed the nsp14 protein in Escherichia coli, and characterized the nature and the role(s) of the metal ions in the reaction chemistry.
Ping, Chen +5 more
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PLoS ONE, 2018 Flaviviruses accumulate abundant subgenomic RNA (sfRNA) in infected cells. It has been reported that sfRNA results from stalling of host 5'-to-3' exoribonuclease XRN1 at the highly structured RNA of the 3' untranslated region (UTR).
Yi-Shiuan Chen +4 more
doaj +1 more source
Suppression of Viral RNA Recombination by a Host Exoribonuclease [PDF]
Journal of Virology, 2006 ABSTRACT RNA viruses of humans, animals, and plants evolve rapidly due to mutations and RNA recombination. A previous genome-wide screen in Saccharomyces cerevisiae , a model host, identified five host genes, including XRN1 , encoding a 5′-3′ exoribonuclease, whose absence led to an
Chi-Ping, Cheng +2 more
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An essential function for the phosphate-dependent exoribonucleases RNase PH and polynucleotide phosphorylase [PDF]
, 1997 Escherichia coli cells lacking both polynucleotide phosphorylase (PNPase) and RNase PH, the only known P(i)-dependent exoribonucleases, were previously shown to grow slowly at 37 degrees C and to display a dramatically reduced level of tRNA(Tyr)su3 ...
Zhou, Z, Deutscher, M P
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Oligoribonuclease is distinct from the other known exoribonucleases of Escherichia coli [PDF]
, 1995 Oligoribonuclease, an exoribonuclease specific for small oligoribonucleotides, was initially characterized 20 years ago (S. K. Niyogi and A. K. Datta, J. Biol. Chem.
Yu, D, Deutscher, M P
core +1 more source
Bio-Protocol, 2012 Polyadenylation is a post-transcriptional modification of RNA occurring in prokaryotes, eukaryotes and organelles. However, the function and extent of bacterial polyadenylation are in marked contrast to those of eukaryotic poly(A) tails.
Eliane Hajnsdorf
doaj +1 more source
Viral silencing suppressors and cellular proteins partner with plant RRP6-like exoribonucleases [PDF]
, 2020 RNA silencing and RNA decay are functionally interlaced, regulate gene expression and play a pivotal role in antiviral responses. As a counter defensive strategy, many plant and mammalian viruses encode suppressors which interfere with both mechanisms ...
Freire, Miguel Angel
core +1 more source
Composition and function of P bodies in Arabidopsis thaliana
Frontiers in Plant Science, 2014 mRNA accumulation is tightly regulated by diverse molecular pathways. The identification and characterization of enzymes and regulatory proteins involved in controlling the fate of mRNA offers the possibility to broaden our understanding of ...
Luis David Maldonado-Bonilla
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Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product. [PDF]
PLoS ONE, 2013 In eukaryotes, the exosome plays a central role in RNA maturation, turnover, and quality control. In Saccharomyces cerevisiae, the core exosome is composed of nine catalytically inactive subunits constituting a ring structure and the active nuclease ...
Filipa P Reis +8 more
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Unifying the features that determine substrate preferences of nanoRNases [PDF]
, 2021 205 pagesRNA polymers are synthesized, degraded, and modified through several varied cellular processes. The ability of cells to degrade and recycle their RNA products is a ubiquitous and essential function. Specific subsets of endo- and exoribonucleases
Lormand, Justin
core +1 more source