Results 61 to 70 of about 6,830 (257)

Regulation of cytoplasmic RNA stability: lessons from drosophila [PDF]

, 2018
The process of RNA degradation is a critical level of regulation contributing to the control of gene expression. In the last two decades a number of studies have shown the specific and targeted nature of RNA decay and its importance in maintaining ...
Abdelmohsen, Allmang, Ameres, An, Antic, Astuti, Baccarini, Bakheet, Bakheet, Bakheet, Bassett, Bazzini, Berezikov, Bitetti, Boczonadi, Bonneau, Bortolamiol-Becet, Braun, Brown, Burroughs, Cairrao, Cairrao, Callahan, Carballo, Chang, Chang, Chapman, Chapman, Cheadle, Chen, De Almeida, De Lella Ezcurra, Decker, Di Donato, Ding, Duffy, Eberle, Eckmann, Eggens, Eulalio, Faehnle, Fenger-Gron, Forstemann, Frazao, Garneau, Gatfield, Graham, Graham, Grima, Groen, Gudipati, Haas, Hales, Han, Han, Heo, Hopkins, Hou, Iwasaki, Jonas, Jones, Jones, Jones, Juvvuna, Kaberdin, Kadaba, Kahvejian, Katoh, Kim, Kim, Kinoshita, Kiss, Kowalinski, Larimer, Lebreton, Lee, Li, Lim, Lin, Liu, Londin, Lowell, Lubas, Makino, Malecki, Malet, Mamolen, Marin-Vicente, Maryati, Mata, Mitchell, Modepalli, Molleston, Moon, Morris, Mullen, Murakami, Murray, Nagarajan, Newbury, Ng, Nishioka, Ohkura, Okada, Orban, Pandey, Park, Pashler, Peng, Perez-Ortin, Pfeiffer, Pirouz, Preker, Presnyak, Rehwinkel, Reimao-Pinto, Reimao-Pinto, Reis, Reiter, Rissland, Rose, Russo, Schaeffer, Schaeffer, Schaeffer, Schertel, Schneider, Schneider, Schneider, Schoenberg, Sharif, Sinturel, Smith, Snee, Spasic, Staals, Steinbrunn, Suh, Synowsky, Temme, Temme, Tharun, Thomas, Till, Tomari, Tomecki, Tomecki, Towler, Towler, Towler, Ustianenko, Vallejo, Vindry, Wahle, Waldron, Wan, Wasmuth, Wei, Wells, Wolf, Wyers, Wyman, Yamashita, Zabolotskaya, Zhang   +164 more
core   +1 more source

Polyadenylated RNA Sampling

Bio-Protocol, 2012
Polyadenylation is a post-transcriptional modification of RNA occurring in prokaryotes, eukaryotes and organelles. However, the function and extent of bacterial polyadenylation are in marked contrast to those of eukaryotic poly(A) tails.
Eliane Hajnsdorf
doaj   +1 more source

Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. [PDF]

, 2018
A family of DEDDh 3'→5' exonucleases known as Small RNA Degrading Nucleases (SDNs) initiates the turnover of ARGONAUTE1 (AGO1)-bound microRNAs in Arabidopsis by trimming their 3' ends. Here, we report the crystal structure of Arabidopsis SDN1 (residues 2-
Cao, Chunyang, Chen, Jiayi, Chen, Xuemei, Gan, Jianhua, Gu, Jiaqi, Huang, Ying, Liu, Li, Ma, Jinbiao, Ruan, Wenjie, You, Chenjiang, Zhang, Lu   +10 more
core   +2 more sources

RNA turnover: The helicase story unwinds [PDF]

, 1996
Recent results show that RNA helicases play important roles in RNA decay, both as exoribonuclease accessory factors and in communicating signals to RNA decay ...
Jacobs Anderson, John S, Parker, Roy
core   +1 more source

Composition and function of P bodies in Arabidopsis thaliana

Frontiers in Plant Science, 2014
mRNA accumulation is tightly regulated by diverse molecular pathways. The identification and characterization of enzymes and regulatory proteins involved in controlling the fate of mRNA offers the possibility to broaden our understanding of ...
Luis David Maldonado-Bonilla
doaj   +1 more source

Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product. [PDF]

PLoS ONE, 2013
In eukaryotes, the exosome plays a central role in RNA maturation, turnover, and quality control. In Saccharomyces cerevisiae, the core exosome is composed of nine catalytically inactive subunits constituting a ring structure and the active nuclease ...
Filipa P Reis, Ana Barbas, A A Klauer-King, Borislava Tsanova, Daneen Schaeffer, Eduardo López-Viñas, Paulino Gómez-Puertas, Ambro van Hoof, Cecília M Arraiano   +8 more
doaj   +1 more source

Circular RNA as a Potential Biomarker for Forensic Age Prediction

Frontiers in Genetics, 2022
In forensic science, accurate estimation of the age of a victim or suspect can facilitate the investigators to narrow a search and aid in solving a crime.
Junyan Wang, Chunyan Wang, Yangyan Wei, Yanhao Zhao, Can Wang, Chaolong Lu, Jin Feng, Shujin Li, Bin Cong   +8 more
doaj   +1 more source

Supporting Role for GTPase Rab27a in Hepatitis C Virus RNA Replication through a Novel miR-122-Mediated Effect. [PDF]

PLoS Pathogens, 2015
The small GTPase Rab27a has been shown to control membrane trafficking and microvesicle transport pathways, in particular the secretion of exosomes. In the liver, high expression of Rab27a correlates with the development of hepatocellular carcinoma.
Tzu-Chun Chen, Chung-Han Hsieh, Peter Sarnow   +2 more
doaj   +1 more source

Alterations of the Transcriptome of Sulfolobus acidocaldarius by Exoribonuclease aCPSF2

PLoS ONE, 2013
Recent studies identified a 5´ to 3´ exoribonuclease termed Sso-RNase J in the crenarchaeon Sulfolobus solfataricus (Sso), which has been reclassified to the aCPSF2 (archaeal cleavage and polyadenylation specificity factor 2) group of β-CASP proteins. In this study, the Sso-aCPSF2 orthologue of Sulfolobus acidocaldarius (Saci-aCPSF2) was functionally ...
Salim Manoharadas, Udo Bläsi, Lukas Zeichen, Birgit Märtens, Ivo L. Hofacker, Fabian Amman, Fabian Amman, Sonja-Verena Albers, Alvaro Orell   +8 more
openaire   +8 more sources

Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing [PDF]

, 2006
Besides linear RNAs, pre-mRNA splicing generates three forms of RNAs: lariat introns, Y-structure introns from trans-splicing, and circular exons through exon skipping.
Malhotra, Arun, Mayeda, Akila, Suzuki, Hitoshi, Wang, Jinhua, Zhang, Michael Q., Zuo, Yuhong   +5 more
core   +6 more sources