Results 1 to 10 of about 97,752 (283)
Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]
Mediators of Inflammation, 2016 Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM +5 more
core +11 more sources
Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis [PDF]
Cells, 2020 Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC ...
Kyong-Oh Shin +19 more
doaj +3 more sources
Scientific Reports, 2022 Improved risk stratification of patients suspected of prostate cancer prior to biopsy continues to be an unmet clinical need. ExoDx Prostate (IntelliScore) “EPI” is a non-invasive urine test utilizing RNA from exosomes to provide a risk score that ...
Alexander Kretschmer +18 more
doaj +1 more source
Circulation Research, 2015 Nature has designed clever ways for information and material transfer between cells and for intercellular coordination. Mechanisms include direct cell contact, gap junctions, and receptor-ligand signaling. In the past decade, a particular form of exchange has gained increasing attention, and that is intercellular transfer of extracellular vesicles ...
Yin, Tintut, Linda L, Demer
openaire +5 more sources
npj Microgravity, 2022 Molecular profiling to characterize the effects of environmental exposures is important from the human health and performance as well as the occupational medicine perspective in space exploration.
Sudipto K. Chakrabortty +11 more
doaj +1 more source
Pharmaceutics, 2022 According to clinical studies, statins improve the efficacy of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) blockade therapy for breast cancer; however, the underlying mechanisms are unclear.
Eun-Ji Choe +5 more
doaj +1 more source
Cells, 2021 Ovarian cancer (OC) is one of the most diagnosed gynecological cancers in women. Due to the lack of effective early stage screening, women are more often diagnosed at an advanced stage; therefore, it is associated with poor patient outcomes.
Priyakshi Kalita-de Croft +4 more
doaj +1 more source
The Scientific World JOURNAL, 2009 Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responsesin vivo.
Irena Dimov +2 more
openaire +3 more sources
A SARS-CoV-2 antigen rapid diagnostic test for resource limited settings
Scientific Reports, 2021 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19 disease. RT-qPCR has been the primary method of diagnosis; however, the required infrastructure is lacking in many developing countries and the virus has ...
Erica Frew +8 more
doaj +1 more source
EMBnet.journal, 2020 Extracellular vesicles have been the focus of a large number of studies in the past five years. Exosomes, a subgroup of extracellular vesicles, are of particularly high interest because they partake in a wide number of biological pathways. Produced by a variety of cells, exosomes have an important role in both physiological and pathological conditions.
Mitsis, Thanasis +6 more
openaire +4 more sources