Results 11 to 20 of about 168,932 (404)
The exosome journey: from biogenesis to uptake and intracellular signalling
Cell Communication and Signaling, 2021 The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials testing exosomes for diagnostic and therapeutic applications are generating remarkable interest from the scientific community and investors.
Sonam Gurung +3 more
doaj +2 more sources
Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery [PDF]
Pharmaceutics, 2018 The similarities between exosomes and liposomes, together with the high organotropism of several types of exosomes, have recently prompted the development of engineered-exosomes or exosome-mimetics, which may be artificial (liposomal) or cell-derived ...
S. Antimisiaris +2 more
semanticscholar +8 more sources
Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function
Genomics, Proteomics & Bioinformatics, 2015 Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell types into the extracellular space. Such vesicles are widely distributed in various body fluids. Recently, mRNAs and microRNAs (miRNAs) have been identified in exosomes, which can be taken up by neighboring or distant cells and subsequently modulate ...
Jian Zhang +6 more
semanticscholar +4 more sources
Exosomes and Atherogenesis [PDF]
Frontiers in Cardiovascular Medicine, 2021 Myocardial infarction and ischemic stroke are the leading causes of mortality worldwide. Atherosclerosis is their common pathological foundation. It is known that atherosclerosis is characterized by endothelial activation/injury, accumulation of inflammatory immune cells and lipid-rich foam cells, followed by the development of atherosclerotic plaque ...
Bingbing Lin +5 more
openaire +4 more sources
Exosome engineering in cell therapy and drug delivery
InflammoPharmacology, 2023 Cell-derived exosomes have opened new horizons in modern therapy for advanced drug delivery and therapeutic applications, due to their key features such as low immunogenicity, high physicochemical stability, capacity to penetrate into tissues, and the ...
Somaye Sadeghi +4 more
semanticscholar +1 more source
Current Strategies for Exosome Cargo Loading and Targeting Delivery
Cells, 2023 Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in diameter, possess a lipid bilayer and are secreted by various cells.
Haifeng Zeng +5 more
semanticscholar +1 more source
Exosome-Based Smart Drug Delivery Tool for Cancer Theranostics
ACS Biomaterials Science & Engineering, 2023 Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles derived from the plasma membrane. The main activity of exosomes is cellular communication.
Rishav Kar +12 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic inflammation upon binding to pattern recognition receptors. Exosomes are endosome-derived vesicles, which carry proteins, lipids and nucleic acids, and facilitate intercellular
Atsushi Murao +6 more
openaire +4 more sources
Review on Strategies and Technologies for Exosome Isolation and Purification
Frontiers in Bioengineering and Biotechnology, 2022 Exosomes, a nano-sized subtype of extracellular vesicles secreted from almost all living cells, are capable of transferring cell-specific constituents of the source cell to the recipient cell.
Jiaci Chen +6 more
semanticscholar +1 more source