Results 11 to 20 of about 182,132 (342)
The exosome journey: from biogenesis to uptake and intracellular signalling
Cell communication and signaling : CCS, 2021 The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials testing exosomes for diagnostic and therapeutic applications are generating remarkable interest from the scientific community and investors.
Sonam Gurung +3 more
semanticscholar +1 more source
Exosome engineering in cell therapy and drug delivery
InflammoPharmacology, 2023 Cell-derived exosomes have opened new horizons in modern therapy for advanced drug delivery and therapeutic applications, due to their key features such as low immunogenicity, high physicochemical stability, capacity to penetrate into tissues, and the ...
Somaye Sadeghi +4 more
semanticscholar +1 more source
Current Strategies for Exosome Cargo Loading and Targeting Delivery
Cells, 2023 Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in diameter, possess a lipid bilayer and are secreted by various cells.
Haifeng Zeng +5 more
semanticscholar +1 more source
Exosome-Based Smart Drug Delivery Tool for Cancer Theranostics
ACS Biomaterials Science & Engineering, 2023 Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles derived from the plasma membrane. The main activity of exosomes is cellular communication.
Rishav Kar +12 more
semanticscholar +1 more source
Exosome-Based Drug Delivery: Translation from Bench to Clinic
Pharmaceutics, 2023 Exosome-based drug delivery is emerging as a promising field with the potential to revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles released by various cell types, have attracted significant attention due to their
Hee Byung Koh +3 more
semanticscholar +1 more source
Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
Molecular Cancer, 2022 Exosomes are well-known key mediators of intercellular communication and contribute to various physiological and pathological processes. Their biogenesis involves four key steps, including cargo sorting, MVB formation and maturation, transport of MVBs ...
Qing-fang Han +6 more
semanticscholar +1 more source
Exosome Processing and Characterization Approaches for Research and Technology Development
Advancement of science, 2022 Exosomes are extracellular vesicles that share components of their parent cells and are attractive in biotechnology and biomedical research as potential disease biomarkers as well as therapeutic agents.
James J. Lai +11 more
semanticscholar +1 more source
Review on Strategies and Technologies for Exosome Isolation and Purification
Frontiers in Bioengineering and Biotechnology, 2022 Exosomes, a nano-sized subtype of extracellular vesicles secreted from almost all living cells, are capable of transferring cell-specific constituents of the source cell to the recipient cell.
Jiaci Chen +6 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Mesenchymal stem cell small extracellular vesicles (MSC-sEVs) are a priority for researchers because of their role in tissue regeneration. sEVs act as paracrine factors and carry various cargos, revealing the state of the parent cells and contributing to
Yuting Tang +9 more
doaj +1 more source
Cells, 2020 Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication. With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the characteristics of producer cells, exosomes can be utilized as cell-free ...
Dae Hyun Ha +11 more
doaj +1 more source