Results 21 to 30 of about 83,398 (334)
Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responsesin vivo.
Irena Dimov+2 more
openaire +3 more sources
Studies have shown that stem cells and their derivatives, including conditioned media (CM), have inhibitory effects on skin pigmentation. However, evidence supporting the skin brightening effect of exosomes derived from stem cells is lacking.
Byong Seung Cho+14 more
doaj +1 more source
We describe the events surrounding the identification of the exosome complex and the subsequent early development of the field. Like many scientific discoveries, the initial identification and characterization ofthe exosome was based on a combination of skill, good fortune--and the availability of cutting edge technology.
Phil Mitchell, David Tollervey
openaire +4 more sources
Acute kidney injury, AKI, is relatively common in the hospital setting, and beyond the identification of the underlying cause and supportive measures, little can be done to facilitate healing of the compromised kidney.
Christopher J. Ward+1 more
openaire +3 more sources
Exosomes are nano-sized vesicles (30–200 nm) constantly released by almost all cells. The ability of exosomes to travel between cells and deliver their cargo, which includes lipids, proteins, and nucleic acids, makes them an appealing cell-free therapy ...
Byong Seung Cho+3 more
doaj +1 more source
Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
openaire +4 more sources
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC ...
Kyong-Oh Shin+19 more
doaj +1 more source
Quantification of Exosomes [PDF]
Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology.
Robert A. Star+3 more
openaire +3 more sources
The role of the Arabidopsis Exosome in siRNA-independent silencing of heterochromatic loci. [PDF]
The exosome functions throughout eukaryotic RNA metabolism and has a prominent role in gene silencing in yeast. In Arabidopsis, exosome regulates expression of a "hidden" transcriptome layer from centromeric, pericentromeric, and other heterochromatic ...
Jun-Hye Shin+5 more
doaj +1 more source
Ascorbate peroxidase‐mediated in situ labelling of proteins in secreted exosomes
The extracellular vesicle exosome mediates intercellular communication by transporting macromolecules such as proteins and ribonucleic acids (RNAs). Determining cargo contents with high accuracy will help decipher the biological processes that exosomes ...
Byung Rho Lee+7 more
doaj +1 more source