Results 21 to 30 of about 97,752 (283)
Extracellular vesicles from plasma have higher tumour RNA fraction than platelets
Journal of Extracellular Vesicles, 2020 In addition to Circulating Tumour Cells (CTCs), cell-free DNA (cfDNA) and Extracellular Vesicles (EVs), the notion of “Tumour-Educated Platelets” (TEP) has recently emerged as a potential source of tumour-derived biomarkers accessible through blood ...
Kay Brinkman +6 more
doaj +1 more source
Cells, 2020 Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication. With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the characteristics of producer cells, exosomes can be utilized as cell-free ...
Dae Hyun Ha +11 more
doaj +1 more source
Exosome-Based Smart Drug Delivery Tool for Cancer Theranostics
ACS Biomaterials Science & Engineering, 2023 Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles derived from the plasma membrane. The main activity of exosomes is cellular communication.
Rishav Kar +12 more
semanticscholar +1 more source
Exosome-Based Drug Delivery: Translation from Bench to Clinic
Pharmaceutics, 2023 Exosome-based drug delivery is emerging as a promising field with the potential to revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles released by various cell types, have attracted significant attention due to their
Hee Byung Koh +3 more
semanticscholar +1 more source
Tumour exosome integrins determine organotropic metastasis
Nature, 2015 Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, liver- and brain-tropic tumour cells fuse preferentially with resident ...
Ayuko Hoshino +53 more
semanticscholar +1 more source
Regulation of exosome production and cargo sorting
International Journal on Biological Sciences, 2021 Cellular communication can be mediated by the exchange of biological information, mainly in the form of proteins and RNAs. This can occur when extracellular vesicles, such as exosomes, secreted by a donor cell are internalized by an acceptor cell ...
Hong Wei +11 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Loading human umbilical mesenchymal stem cell (hUMSC) derived exosomes onto hydrogel scaffolds is a strategy for rapid wound healing. The clinical application of exosomes is hindered by low production, and exosome mimetics could be substituted for ...
Jie Zhu +12 more
doaj +1 more source
A new yeast poly(A) polymerase complex involved in RNA quality control [PDF]
, 2005 Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Štěpánka Vaňáčová +71 more
core +4 more sources
Future Science OA, 2021 Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
openaire +3 more sources
Reassessment of Exosome Composition.
Cell, 2019 The heterogeneity of small extracellular vesicles and presence of non-vesicular extracellular matter have led to debate about contents and functional properties of exosomes.
D. K. Jeppesen +14 more
semanticscholar +1 more source