Results 21 to 30 of about 143,013 (333)

Hallmarks of Exosomes

open access: yesFuture Science OA, 2021
Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
openaire   +3 more sources

Exosomes

open access: yesAnnual Review of Biochemistry, 2019
Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, nucleic acids, and glycoconjugates. Exosomes contain an array of membrane-associated, high-order oligomeric protein complexes, display pronounced molecular heterogeneity, and are ...
Pegtel, D. Michiel, Gould, Stephen J.
openaire   +3 more sources

Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis

open access: yesStem Cell Research & Therapy, 2018
Exosomes are nano-sized vesicles (30–200 nm) constantly released by almost all cells. The ability of exosomes to travel between cells and deliver their cargo, which includes lipids, proteins, and nucleic acids, makes them an appealing cell-free therapy ...
Byong Seung Cho   +3 more
doaj   +1 more source

Skin Brightening Efficacy of Exosomes Derived from Human Adipose Tissue-Derived Stem/Stromal Cells: A Prospective, Split-Face, Randomized Placebo-Controlled Study

open access: yesCosmetics, 2020
Studies have shown that stem cells and their derivatives, including conditioned media (CM), have inhibitory effects on skin pigmentation. However, evidence supporting the skin brightening effect of exosomes derived from stem cells is lacking.
Byong Seung Cho   +14 more
doaj   +1 more source

Exosomes and Atherogenesis [PDF]

open access: yesFrontiers in Cardiovascular Medicine, 2021
Myocardial infarction and ischemic stroke are the leading causes of mortality worldwide. Atherosclerosis is their common pathological foundation. It is known that atherosclerosis is characterized by endothelial activation/injury, accumulation of inflammatory immune cells and lipid-rich foam cells, followed by the development of atherosclerotic plaque ...
Bingbing Lin   +5 more
openaire   +3 more sources

Digital detection of exosomes by interferometric imaging [PDF]

open access: yes, 2016
Exosomes, which are membranous nanovesicles, are actively released by cells and have been attributed to roles in cell-cell communication, cancer metastasis, and early disease diagnostics.
Benussi, Luisa   +13 more
core   +2 more sources

Cryo-self-assembled silk fibroin sponge as a biodegradable platform for enzyme-responsive delivery of exosomes

open access: yesBioactive Materials, 2022
Although advances in protein assembly preparation have provided a new platform for drug delivery during tissue engineering, achieving long-term controlled exosome delivery remains a significant challenge. Diffusion-dominated exosome release using protein
Muyang Sun   +11 more
doaj   +1 more source

The role of the Arabidopsis Exosome in siRNA-independent silencing of heterochromatic loci. [PDF]

open access: yesPLoS Genetics, 2013
The exosome functions throughout eukaryotic RNA metabolism and has a prominent role in gene silencing in yeast. In Arabidopsis, exosome regulates expression of a "hidden" transcriptome layer from centromeric, pericentromeric, and other heterochromatic ...
Jun-Hye Shin   +5 more
doaj   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

open access: yes, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core   +1 more source

Exosomes released from breast cancer carcinomas stimulate cell movement [PDF]

open access: yes, 2015
For metastasis to occur cells must communicate with to their local environment to initiate growth and invasion. Exosomes have emerged as an important mediator of cell-to-cell signalling through the transfer of molecules such as mRNAs, microRNAs, and ...
Gucek, Marjan   +5 more
core   +8 more sources

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