Results 31 to 40 of about 143,013 (333)

Cell Propagation of Cholera Toxin CTA ADP-Ribosylating Factor by Exosome Mediated Transfer [PDF]

, 2018
In this study, we report how the cholera toxin (CT) A subunit (CTA), the enzyme moiety responsible for signaling alteration in host cells, enters the exosomal pathway, secretes extracellularly, transmits itself to a cell population.
Boussadia, Zaira, Carollo, Maria, Fabbri, Alessia, Falchi, Mario, Fecchi, Katia, Fiani, Maria Luisa, Gallina, Angelo, Palermo, Angela, Parisi, Sofia, Pasquini, Luca, Sargiacomo, Massimo, Zanetti, Cristiana   +11 more
core   +1 more source

Ascorbate peroxidase‐mediated in situ labelling of proteins in secreted exosomes

Journal of Extracellular Vesicles, 2022
The extracellular vesicle exosome mediates intercellular communication by transporting macromolecules such as proteins and ribonucleic acids (RNAs). Determining cargo contents with high accuracy will help decipher the biological processes that exosomes ...
Byung Rho Lee, Tae Jin Lee, Sekyung Oh, Chenglong Li, Jin‐Hyuk A Song, Brendan Marshall, Wenbo Zhi, Sang‐Ho Kwon   +7 more
doaj   +1 more source

Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. [PDF]

, 2020
Exosomes are nanovesicles secreted by virtually all cells. Exosomes mediate the horizontal transfer of various macromolecules previously believed to be cell-autonomous in nature, including nonsecretory proteins, various classes of RNA, metabolites, and ...
Anderson, Johnathon D, Elahi, Fanny M, Farwell, D Gregory, Nolta, Jan A   +3 more
core  

Exosome-delivered microRNAs promote IFN-α secretion by human plasmacytoid DCs via TLR7 [PDF]

, 2018
The excessive production of type I IFNs is a hallmark and a main pathogenic mechanism of many autoimmune diseases, including systemic lupus erythematosus (SLE).
Andreoli, Laura, Bergese, Paolo, Bosisio, Daniela, Busatto, Sara, D'Oro, Ugo, Giannello, Veronica, Salvi, Valentina, Sozzani, Silvano, Tincani, Angela, Zingoni, Alessandra   +9 more
core   +1 more source

Nanopillar and nanohole fabrication via mixed lithography

Materials Research Express, 2020
We report a fabrication method for the production of nanopillar (NP) or nanohole (NH) arrays together with a micrometer-sized structure within a single layer.
Seung Hee Baek, Sunwoong Lee, Ju-Hyun Bae, Chang-Won Hong, Mae-Ja Park, Hongsik Park, Moon-Chang Baek, Sung-Wook Nam   +7 more
doaj   +1 more source

A global function for transcription factors in assisting RNA polymerase II termination. [PDF]

, 2017
The role of transcription factors (TFs) on nucleosome positioning, RNA polymerase recruitment, and transcription initiation has been extensively characterized.
Chanfreau, Guillaume F, Roy, Kevin
core   +1 more source

An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency

Journal of Nanobiotechnology, 2022
Background Exosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a bottleneck for clinical translation.
Rongxin Zhang, Te Bu, Ruidan Cao, Zhelong Li, Chen Wang, Bing Huang, Mengying Wei, Lijun Yuan, Guodong Yang   +8 more
doaj   +1 more source

Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]

, 2019
Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C, Duan, Zhenfeng, Feng, Wenlong, Hornicek, Francis J, Shi, Huirong   +4 more
core   +2 more sources

Defined MSC exosome with high yield and purity to improve regenerative activity

Journal of Tissue Engineering, 2021
Exosomes derived from mesenchymal stem cells (MSCs) have been studied as vital components of regenerative medicine. Typically, various isolation methods of exosomes from cell culture medium have been developed to increase the isolation yield of exosomes.
Jun Yong Kim, Won-Kyu Rhim, Yong-In Yoo, Da-Seul Kim, Kyoung-Won Ko, Yun Heo, Chun Gwon Park, Dong Keun Han   +7 more
doaj   +1 more source

Performance Evaluation of BD FACSPresto^TM Near-Patient CD4 Counter for Monitoring Antiretroviral Therapy in HIV-Infected Individuals in Primary Healthcare Clinics in Thailand

Diagnostics, 2022
HIV viral load is more reliable tool for monitoring treatment throughout the course of HIV/AIDS, but the test may be expensive in resource-limited settings. Therefore, enumeration of CD4 T-lymphocyte count remains important in these settings.
Kasama Sukapirom, Somrat Matchua, Charin Thepthai, Narinee Srimark, Ladawan Khowawisetsut, Kovit Pattanapanyasat   +5 more
doaj   +1 more source