Results 31 to 40 of about 168,932 (404)
Frontiers in Bioengineering and Biotechnology, 2022 Loading human umbilical mesenchymal stem cell (hUMSC) derived exosomes onto hydrogel scaffolds is a strategy for rapid wound healing. The clinical application of exosomes is hindered by low production, and exosome mimetics could be substituted for ...
Jie Zhu +12 more
doaj +1 more source
Current Knowledge on Exosome Biogenesis, Cargo-Sorting Mechanism and Therapeutic Implications
Membranes, 2022 Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that can be taken up by recipient cells. The study of EVs has the potential to identify unknown cellular and molecular mechanisms in intercellular communication and ...
Shengkun Xie, Qin Zhang, Li Jiang
semanticscholar +1 more source
, 2010 We describe the events surrounding the identification of the exosome complex and the subsequent early development of the field. Like many scientific discoveries, the initial identification and characterization ofthe exosome was based on a combination of skill, good fortune--and the availability of cutting edge technology.
Phil Mitchell, David Tollervey
openaire +4 more sources
Writing a wrong: Coupled RNA polymerase II transcription and RNA quality control [PDF]
, 2019 Processing and maturation of precursor RNA species is coupled to RNA polymerase II transcription. Co-transcriptional RNA processing helps to ensure efficient and proper capping, splicing, and 3' end processing of different RNA species to help ensure ...
Hughes, Katlyn D. +3 more
core +1 more source
Cells, 2019 The use of extracellular vesicles, specifically exosomes, as carriers of biomarkers in extracellular spaces has been well demonstrated. Despite their promising potential, the use of exosomes in the clinical setting is restricted due to the lack of ...
Laura M Doyle, Michael Zhuo Wang
semanticscholar +1 more source
Future Science OA, 2021 Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
openaire +4 more sources
Cosmetics, 2020 Studies have shown that stem cells and their derivatives, including conditioned media (CM), have inhibitory effects on skin pigmentation. However, evidence supporting the skin brightening effect of exosomes derived from stem cells is lacking.
Byong Seung Cho +14 more
doaj +1 more source
The Exosome Subunit Rrp44 Plays a Direct Role in RNA Substrate Recognition [PDF]
, 2007 The exosome plays key roles in RNA maturation and surveillance, but it is unclear how target RNAs are identified. We report the functional characterization of the yeast exosome component Rrp44, a member of the RNase II family.
Anderson, James T. +2 more
core +2 more sources
International Journal of Nanomedicine, 2020 Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic acids, proteins, lipids and other bioactive substances to play a role in the body’s physiological and pathological processes.
Yi Zhang +5 more
semanticscholar +1 more source
The Scientific World JOURNAL, 2009 Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responsesin vivo.
Irena Dimov +2 more
openaire +3 more sources