Results 31 to 40 of about 70 (70)
Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery [PDF]
Pharmaceutics, 2018 The similarities between exosomes and liposomes, together with the high organotropism of several types of exosomes, have recently prompted the development of engineered-exosomes or exosome-mimetics, which may be artificial (liposomal) or cell-derived vesicles, as advanced platforms for targeted drug delivery.
Sophia G. Antimisiaris +2 more
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Roles of Exosomes and Exosomal MicroRNAs in Postoperative Sleep Disturbance
Nature and Science of Sleep, 2021 Postoperative sleep disturbance (PSD) often occurs in elderly patients after major surgery and exerts harmful effects on postoperative recovery. PSD may increase the incidence of postoperative fatigue, severe anxiety and depression, pain sensitivity, and cognitive dysfunction, which can cause or aggravate neurodegenerative diseases via amyloid ...
Junchao Zhu, Xiangyi Gu
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Exosomes: Mechanisms of Uptake [PDF]
Journal of Circulating Biomarkers, 2015 Exosomes are 30–100 nm microvesicles which contain complex cellular signals of RNA, protein and lipids. Because of this, exosomes are implicated as having limitless therapeutic potential for the treatment of cancer, pregnancy complications, infections, and autoimmune diseases. To date we know a considerable amount about exosome biogenesis and secretion,
Jonathan M. Morris +6 more
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Exosomes and Cardiovascular Protection [PDF]
Cardiovascular Drugs and Therapy, 2016 Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called exosomes. Despite technical challenges in their purification and analysis, exosomes from various sources have been shown to be powerfully cardioprotective.
Davidson, SM, Takov, K, Yellon, DM
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Exosomes in developmental signalling [PDF]
Development, 2016 In order to achieve coordinated growth and patterning during development, cells must communicate with one another, sending and receiving signals that regulate their activities. Such developmental signals can be soluble, bound to the extracellular matrix, or tethered to the surface of adjacent cells.
Ian John McGough, Jean-Paul Vincent
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Roles of exosomes in cardioprotection [PDF]
European Heart Journal, 2016 Exosomes are extracellular vesicles of endosomal origin which have emerged as key mediators of intercellular communication. All major cardiac cell types-including cardiomyocytes, endothelial cells, and fibroblasts-release exosomes that modulate cellular functions.
Barile Lucio +3 more
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Tetherin is an exosomal tether
eLife, 2016 Exosomes are extracellular vesicles that are released when endosomes fuse with the plasma membrane. They have been implicated in various functions in both health and disease, including intercellular communication, antigen presentation, prion transmission, and tumour cell metastasis.
Edgar, James R +4 more
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Connecting Exosomes and Connexins [PDF]
Cancers, 2019 Intercellular communication is accomplished by passage of ions and small molecules through gap junction channels in directly contacting cells or by secretion and response to transmitters, hormones and extracellular vesicles in cells that are distant from each other.
Joanna Gemel +3 more
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The Journal of Cell Biology, 2007 ![][1] Exosomes transport RNA between cells. LOTVALL/MACMILLAN Cells send RNA messages to each other by packing them into tiny membrane vesicles called exosomes, according to Hadi Valadi, Jan Lotvall (Goteborg University, Goteborg, Sweden), and colleagues.
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The role of exosomes and exosomal microRNA in diabetic cardiomyopathy
Frontiers in EndocrinologyDiabetic cardiomyopathy, a formidable cardiovascular complication linked to diabetes, is witnessing a relentless surge in its incidence. Despite extensive research efforts, the primary pathogenic mechanisms underlying this condition remain elusive. Consequently, a critical research imperative lies in identifying a sensitive and dependable marker for ...
Shiyu Gao +4 more
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