Results 41 to 50 of about 97,752 (283)

Exosome: A Review of Its Classification, Isolation Techniques, Storage, Diagnostic and Targeted Therapy Applications

open access: yesInternational Journal of Nanomedicine, 2020
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic acids, proteins, lipids and other bioactive substances to play a role in the body’s physiological and pathological processes.
Yi Zhang   +5 more
semanticscholar   +1 more source

Performance Evaluation of BD FACSPrestoTM Near-Patient CD4 Counter for Monitoring Antiretroviral Therapy in HIV-Infected Individuals in Primary Healthcare Clinics in Thailand

open access: yesDiagnostics, 2022
HIV viral load is more reliable tool for monitoring treatment throughout the course of HIV/AIDS, but the test may be expensive in resource-limited settings. Therefore, enumeration of CD4 T-lymphocyte count remains important in these settings.
Kasama Sukapirom   +5 more
doaj   +1 more source

A global function for transcription factors in assisting RNA polymerase II termination. [PDF]

open access: yes, 2017
The role of transcription factors (TFs) on nucleosome positioning, RNA polymerase recruitment, and transcription initiation has been extensively characterized.
Chanfreau, Guillaume F, Roy, Kevin
core   +1 more source

The role of the Arabidopsis Exosome in siRNA-independent silencing of heterochromatic loci. [PDF]

open access: yesPLoS Genetics, 2013
The exosome functions throughout eukaryotic RNA metabolism and has a prominent role in gene silencing in yeast. In Arabidopsis, exosome regulates expression of a "hidden" transcriptome layer from centromeric, pericentromeric, and other heterochromatic ...
Jun-Hye Shin   +5 more
doaj   +1 more source

Exosome-based liquid biopsies in cancer: opportunities and challenges

open access: yesAnnals of Oncology, 2021
Liquid biopsy in cancer has gained momentum in clinical research and is experiencing a boom for a variety of applications. There are significant efforts to utilize liquid biopsies in cancer for early detection and treatment stratification, as well as ...
W. Yu   +7 more
semanticscholar   +1 more source

Ascorbate peroxidase‐mediated in situ labelling of proteins in secreted exosomes

open access: yesJournal of Extracellular Vesicles, 2022
The extracellular vesicle exosome mediates intercellular communication by transporting macromolecules such as proteins and ribonucleic acids (RNAs). Determining cargo contents with high accuracy will help decipher the biological processes that exosomes ...
Byung Rho Lee   +7 more
doaj   +1 more source

Current knowledge on exosome biogenesis and release

open access: yesCellular and Molecular Life Sciences, 2017
Exosomes are nanosized membrane vesicles released by fusion of an organelle of the endocytic pathway, the multivesicular body, with the plasma membrane.
N. P. Hessvik, A. Llorente
semanticscholar   +1 more source

Nanopillar and nanohole fabrication via mixed lithography

open access: yesMaterials Research Express, 2020
We report a fabrication method for the production of nanopillar (NP) or nanohole (NH) arrays together with a micrometer-sized structure within a single layer.
Seung Hee Baek   +7 more
doaj   +1 more source

Digital detection of exosomes by interferometric imaging [PDF]

open access: yes, 2016
Exosomes, which are membranous nanovesicles, are actively released by cells and have been attributed to roles in cell-cell communication, cancer metastasis, and early disease diagnostics.
Benussi, Luisa   +13 more
core   +2 more sources

Progress, opportunity, and perspective on exosome isolation - efforts for efficient exosome-based theranostics

open access: yesTheranostics, 2020
Exosomes are small extracellular vesicles with diameters of 30-150 nm. In both physiological and pathological conditions, nearly all types of cells can release exosomes, which play important roles in cell communication and epigenetic regulation by ...
Dongbin Yang   +13 more
semanticscholar   +1 more source

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