Results 51 to 60 of about 182,132 (342)
A Quantitative Pharmacology Model of Exosome-Mediated Drug Efflux and Perturbation-Induced Synergy
Pharmaceutics, 2021 Exosomes, naturally occurring vesicles secreted by cells, are undergoing development as drug carriers. We used experimental and computational studies to investigate the kinetics of intracellular exosome processing and exosome-mediated drug efflux and the
Jin Wang +8 more
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The Effects of Exosomes on the Regeneration of Rat Calvaria [PDF]
, 2020 Periodontal disease is a bacterial induced chronic inflammatory condition that occurs in a susceptible host, affecting the teeth, gingiva, periodontal ligament, and alveolar bone.
Beitz, Jill T
core +1 more source
Current knowledge on exosome biogenesis and release
Cellular and Molecular Life Sciences, 2017 Exosomes are nanosized membrane vesicles released by fusion of an organelle of the endocytic pathway, the multivesicular body, with the plasma membrane.
N. P. Hessvik, A. Llorente
semanticscholar +1 more source
Traffic : the International Journal of Intracellular Transport, 2021 Exosomes are extracellular vesicles that in recent years have received special attention for their regulatory functions in numerous biological processes.
Javier Donoso-Quezada +2 more
semanticscholar +1 more source
Cholesterol Regulates Exosome Release in Cultured Astrocytes
Frontiers in Immunology, 2021 Exosomes are vesicles secreted by various kinds of cells, and they are rich in cholesterol, sphingomyelin (SM), phosphatidylcholine, and phosphatidylserine.
Mohammad Abdullah +6 more
doaj +1 more source
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]
, 2018 Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C. +23 more
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The Exosome Subunit Rrp44 Plays a Direct Role in RNA Substrate Recognition [PDF]
, 2007 The exosome plays key roles in RNA maturation and surveillance, but it is unclear how target RNAs are identified. We report the functional characterization of the yeast exosome component Rrp44, a member of the RNase II family.
Anderson, James T. +2 more
core +2 more sources
A proteomic atlas of senescence-associated secretomes for aging biomarker development. [PDF]
, 2020 The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer.
Basisty, Nathan +11 more
core +1 more source
Cardiovascular Diabetology, 2022 Extracellular vesicles are critical mediators of cell communication. They encapsulate a variety of molecular cargo such as proteins, lipids, and nucleic acids including miRNAs, lncRNAs, circular RNAs, and mRNAs, and through transfer of these molecular ...
Valeska Ormazabal +4 more
doaj +1 more source
Nature CommunicationsWound healing is an obvious clinical concern that can be hindered by inadequate angiogenesis, inflammation, and chronic hypoxia. While exosomes derived from adipose tissue-derived stem cells have shown promise in accelerating healing by carrying ...
Xiaoxue Han +5 more
semanticscholar +1 more source